ReviewWorld journal of hepatology2015
Microwave ablation of hepatocellular carcinoma.
Review in World journal of hepatology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03483935 (Microwave Therapy for Treatment of Precancerous Actinic Keratoses), which is not on this map. Cited by 55 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Microwave Therapy for Treatment of Precancerous Actinic Keratoses
Who cites it
55 citing papers in PubMed, 4 syntheses or guidelines pooled it, 120 citations in OpenAlex.
- Impact of microwave ablation on survival rates and recurrence in hepatic malignant tumors.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025Pooled it
- The combination of transcatheter arterial chemoembolisation (TACE) and thermal ablation versus TACE alone for hepatocellular carcinoma.The Cochrane database of systematic reviews · 2022Pooled it
- Liver microwave ablation: a systematic review of various FDA-approved systems.European radiology · 2019Pooled it
- Pooled it
- A feasibility study of microwave therapy for precancerous actinic keratosis.The British journal of dermatology · 2020Trial
- Developing a Better Hepatocellular Carcinoma Treatment: AlEu MOF Nanoparticles Enhance Microwave Thermal Ablation and Synergistically Activate the cGAS-STING Pathway.International journal of nanomedicine · 2026Article
- Review
- Evaluation study of radial and spiral based volumetric thermometry for monitoring of hepatic microwave ablation.Scientific reports · 2025Article
- Recurrent laryngeal nerve thermal injury in radiofrequency ablation for papillary thyroid carcinoma and related risk factors: a prospective large cohort study.European radiology · 2025Article
- Video-Assisted Thoracoscopic Surgery Repair of Diaphragmatic Hernia With Prolene Mesh After Microwave Ablation.Cureus · 2025Article
- Precision oncology: The role of minimally-invasive ablation therapy in the management of solid organ tumors.World journal of radiology · 2025Review
- Microwave ablation for hepatocellular carcinoma in cirrhotic patients with diuretic-resistant ascites.Journal of clinical imaging science · 2025Article
- The relationship between ablation range and ablation energy in papillary thyroid microcarcinoma: a comparison between microwave ablation and laser ablation.European radiology · 2024Article
- Hepatocellular Carcinoma from a Hepatologist's Perspective.Seminars in interventional radiology · 2023Review
- The current landscape of therapies for hepatocellular carcinoma.Carcinogenesis · 2023Review
- Emprint Microwave Thermoablation System: Bridging Thermal Ablation Efficacy between Human Patients and Porcine Models through Mathematical Correlation.Bioengineering (Basel, Switzerland) · 2023Article
- Locoregional Thermal and Chemical Tumor Ablation: Review of Clinical Applications and Potential Opportunities for Use in Low- and Middle-Income Countries.JCO global oncology · 2023Review
- Comparable and Complimentary Modalities for Treatment of Small-Sized HCC: Surgical Resection, Radiofrequency Ablation, and Microwave Ablation.Journal of clinical medicine · 2023Review
- Single-center analysis of percutaneous ablation in the treatment of hepatocellular carcinoma: long-term outcomes of a 7-year experience.Abdominal radiology (New York) · 2023Article
- Case Report: Overcoming challenges in pancreatic cancer with liver metastases: a personalized therapeutic odyssey of TACE, ablation, and immunotherapy.Frontiers in immunology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although surgical resection is still the optimal treatment option for early-stage hepatocellular carcinoma (HCC) in patients with well compensated cirrhosis, thermal ablation techniques provide a valid non-surgical treatment alternative, thanks to their minimal invasiveness, excellent tolerability and safety profile, proven efficacy in local disease control, virtually unlimited repeatability and cost-effectiveness. Different energy sources are currently employed in clinics as physical agents for percutaneous or intra-surgical thermal ablation of HCC nodules. Among them, radiofrequency (RF) currents are the most used, while microwave ablations (MWA) are becoming increasingly popular. Starting from the 90s', RF ablation (RFA) rapidly became the standard of care in ablation, especially in the treatment of small HCC nodules; however, RFA exhibits substantial performance limitations in the treatment of large lesions and/or tumors located near major heat sinks. MWA, first introduced in the Far Eastern clinical practice in the 80s', showing promising results but also severe limitations in the controllability of the emitted field and in the high amount of power employed for the ablation of large tumors, resulting in a poor coagulative performance and a relatively high complication rate, nowadays shows better results both in terms of treatment controllability and of overall coagulative performance, thanks to the improvement of technology. In this review we provide an extensive and detailed overview of the key physical and technical aspects of MWA and of the currently available systems, and we want to discuss the most relevant published data on MWA treatments of HCC nodules in regard to clinical results and to the type and rate of complications, both in absolute terms and in comparison with RFA.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.