Evidence map›Paper›PMID 26557882›Full record

ReviewEcancermedicalscience2015

Medical treatment of early stage and rare histological variants of epithelial ovarian cancer.

Nicoletta Tomasi Cont, Annamaria Ferrero, Fedro Alessandro Peccatori, Marta D'Alonzo, Giovanni Codacci-Pisanelli, Nicoletta Colombo, Nicoletta Biglia

Abstract readReview
In one paragraph

Review in Ecancermedicalscience, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
  4. Review
  5. Endometriosis: A Malignant Fingerprint.Journal of cancer research and therapeutic oncology · 2020
    Article
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nicoletta Tomasi ContAcademic Division of Gynaecology and Obstetrics, Mauriziano Hospital, University of Turin, Italy.
Annamaria FerreroAcademic Division of Gynaecology and Obstetrics, Mauriziano Hospital, University of Turin, Italy.
Fedro Alessandro PeccatoriFertility and Pregnancy Unit, Medical Gynaecologic Oncology Division, European Institute of Oncology, Milan, Italy.
Marta D'AlonzoAcademic Division of Gynaecology and Obstetrics, Mauriziano Hospital, University of Turin, Italy.
Giovanni Codacci-PisanelliFertility and Pregnancy Unit, Medical Gynaecologic Oncology Division, European Institute of Oncology, Milan, Italy ; Department of Medical and Surgical Science and Biotechnology, University of Rome 'La Sapienza', Italy.
Nicoletta ColomboMedical Gynaecologic Oncology Division, European Institute of Oncology, University of Milan-Bicocca, Italy.
Nicoletta BigliaAcademic Division of Gynaecology and Obstetrics, Mauriziano Hospital, University of Turin, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epithelial ovarian cancer is often considered a single pathological entity, but increasing evidence suggests that it is rather a group of different neoplasms, each with unique pathological characteristics, molecular features, and clinical behaviours. This heterogeneity accounts for the different sensitivity to antineoplastic drugs and makes the treatment of ovarian tumours a challenge. For early-stage disease, as well as for heavily pre-treated patients with recurrent ovarian cancer, the benefit of chemotherapy remains uncertain. Clear-cell, mucinous, low-grade serous, and endometrioid carcinomas show different molecular characteristics, which require different therapeutic approaches. In the era of personalised cancer medicine, understanding the pathogenesis and the genetic background of each subtype of epithelial ovarian tumour may lead to a tailored therapy, maximising the benefits of specific treatments and possibly reducing the side effects. Furthermore, personal factors, such as the patient's performance status, should be taken into account in the management of ovarian cancer, with the aim of safeguarding the patients' quality of life.

Indexed as

biological markersovarian neoplasmpersonalised medicine

Identifiers

PMID26557882
PMCPMC4631577

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.