ReviewBioMed research international2015
Effects of Physical (In)activity on Platelet Function.
Review in BioMed research international, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
58 citing papers in PubMed, 2 syntheses or guidelines pooled it, 111 citations in OpenAlex.
- Periodontitis and Platelets Status: A Systematic Review With Meta-Analysis and Trial Sequential Analysis.Journal of periodontal research · 2025Pooled it
- Physical activity and risk of venous thromboembolism: systematic review and meta-analysis of prospective cohort studies.European journal of epidemiology · 2020Pooled it
- Intensity matters: high-intensity interval resistance exercise induces greater immune activation than low-intensity resistance exercise 45 min post-workout.European journal of applied physiology · 2026Trial
- Time of day influences caffeine's effects on exercise-induced haemostatic responses in sedentary young men: a randomized crossover trial.European journal of clinical nutrition · 2026Trial
- Intelligent circuit exercise training improves platelet mitochondrial bioenergetic efficiency in sedentary men.European journal of applied physiology · 2026Trial
- Multi-omics uncovers immune-modulatory molecules in plasma contributing to resistance exercise-ameliorated locomotor disability after incomplete spinal cord injury.Genome medicine · 2025Trial
- Influence of cardiopulmonary exercise test on platelet function in patients with coronary artery diseases on antiplatelet therapy.BMC cardiovascular disorders · 2022Trial
- Physical exertion as a trigger of acute coronary syndrome caused by plaque erosion.Journal of thrombosis and thrombolysis · 2020Trial
- Trial
- The response of intercellular adhesion molecule-1 to exhaustive submaximal exercise and its correlation with physiological and anthropometric measures.Journal of medicine and lifeTrial
- The effect of physical activity on growth factor concentrations in platelet-rich fibrin: a cross-sectional study.Journal of applied oral science : revista FOB · 2026Article
- Dietary Fat Intake and Indices of Blood Profiles in High-Performance Athletes: An Exploratory Study Focusing on Platelet Variables.Nutrients · 2025Article
- Effect of training on physiological, hematological, and chemical parameters in Belgian Malinois Dogs in Indonesia's tropical climate.Open veterinary journal · 2025Article
- Low functional capacity in peripheral artery disease is associated with increased platelet activity and cardiovascular events.Atherosclerosis · 2025Article
- Differential effects of intermittent anaerobic exercise on haematological parameters during and outside Ramadan.Journal of public health in Africa · 2025Article
- Impact of physical activity on maternal and neonatal outcomes among women with vaginal births-single center prospective cohort study.Frontiers in medicine · 2025Article
- Low-Intensity Resistance Exercise in Cardiac Rehabilitation: A Narrative Review of Mechanistic Evidence and Clinical Implications.Journal of clinical medicine · 2024Review
- Acute Effects of Kickboxing K1 Matches on Hematological Parameters of Kickboxers.Journal of functional morphology and kinesiology · 2024Article
- The possible role of the vasopressin system in hematopoiesis.Scientific reports · 2024Article
- Effect of Regular Training on Platelet Function in Untrained Thoroughbreds.Animals : an open access journal from MDPI · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
As platelet activation is closely related to the liberation of growth factors and inflammatory mediators, platelets play a central role in the development of CVD. Virtually all cardiovascular risk factors favor platelet hyperreactivity and, accordingly, also physical (in)activity affects platelet function. Within this paper, we will summarize and discuss the current knowledge on the impact of acute and habitual exercise on platelet function. Although there are apparent discrepancies regarding the reported effects of acute, strenuous exercise on platelet activation, a deeper analysis of the available literature reveals that the applied exercise intensity and the subjects' cardiorespiratory fitness represent critical determinants for the observed effects. Consideration of these factors leads to the summary that (i) acute, strenuous exercise can lead to platelet activation, (ii) regular physical activity and/or physical fitness diminish or prevent platelet activation in response to acute exercise, and (iii) habitual physical activity and/or physical fitness also favorably modulate platelet function at physical rest. Notably, these effects of exercise on platelet function show obvious similarities to the well-recognized relation between exercise and the risk for cardiovascular events where vigorous exercise transiently increases the risk for myocardial infarction and a physically active lifestyle dramatically reduces cardiovascular mortality.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.