ArticleWorld journal of critical care medicine2015
Deep sternal wound infection after cardiac surgery: Evidences and controversies.
Article in World journal of critical care medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 32 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of Platelet Rich Fibrin (PRF) in Treatment of Non-healing Sternum Wound After Open-heart Surgery
Efficacy of Diluted Betadine vs Antibiotic Installation Before Surgical Wound Closure in Prevention of Post Cardiac Surgery Wound Infection
Who cites it
32 citing papers in PubMed, 98 citations in OpenAlex.
- Investigating Titanium Fastener Technology: Results from the Multi-center Prospective CRIMP Study.Advances in therapy · 2026Observational
- Modifiable Perioperative Practices for the Prevention of Postoperative Complications After Cardiac Surgery: A Narrative Review.Medicina (Kaunas, Lithuania) · 2026Review
- Surgical management of complex mediastinitis: an 8-year single-centre experience reinforcing the role of open thoracotomy.Interdisciplinary cardiovascular and thoracic surgery · 2025Article
- Characterisation of Mesenchymal Stromal Cells (MSCs) from Human Adult Thymus as a Potential Cell Source for Regenerative Medicine.Journal of clinical medicine · 2025Article
- Article
- Antibiotic-loaded bone cement fixation technique combined with bilateral pectoralis major muscle flaps tension-free management for sternal infection after midline sternotomy.Journal of cardiothoracic surgery · 2024Article
- Association of HbA1c and utilization of internal mammary arteries with wound infections in CABG.Frontiers in cardiovascular medicine · 2024Article
- Outcomes of Coronary Artery Bypass Graft Surgery in Africa: A Systematic Review and Meta-Analysis.Cureus · 2023Review
- Fungal and bacterial co-infection in the superficial and deep sternal wound after open cardiac surgery.Iranian journal of microbiology · 2023Article
- Deep Sternal Wound Infection Following OPCAB: Delving Deeper into the Predisposition!Brazilian journal of cardiovascular surgery · 2023Article
- Predictors of sternal wound infection post cardiac surgery in a Saudi Centre: a case control study.Journal of cardiothoracic surgery · 2023Article
- Intranasal Mupirocin to Reduce Surgical Site Infection Post Cardiac Surgery: A Review of the Literature.Cureus · 2023Review
- Sex-Associated Differences in Short-Term Outcomes in Patients with Deep Sternal Wound Infection after Open-Heart Surgery.Journal of clinical medicine · 2022Article
- Clinical and economic outcomes after sternotomy for cardiac surgery with skin closure through 2-octyl cyanoacrylate plus polymer mesh tape versus absorbable sutures plus waterproof wound dressings: a retrospective cohort study.Journal of cardiothoracic surgery · 2022Observational
- Deep Sternal Wound Infection After Open-heart Cardiac Surgery and Vacuum-Assisted Closure Therapy: a Single-center Study.Medical archives (Sarajevo, Bosnia and Herzegovina) · 2022Observational
- Risk Factors for Deep Sternal Wound Infection after Off-Pump Coronary Artery Bypass Grafting: a Case-Control Study.Brazilian journal of cardiovascular surgery · 2022Article
- Total percutaneous biventricular assist device implantation for fulminant myocarditis.Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs · 2021Article
- In-vitro model for bacterial growth inhibition of compartmentalized infection treated by an ultra-high concentration of antibiotics.PloS one · 2021Article
- Delayed post-traumatic presentation of severe sternal osteomyelitis: A strong multidisciplinary effort and a novel reconstruction technique for a challenging case.Trauma case reports · 2020Article
- Deep sternal wound infection following cardiac surgery: A comparison of the monolateral with the bilateral pectoralis major flaps.International wound journal · 2020Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Despite many advances in prevention and perioperative care, deep sternal wound infection (DSWI) remains a pressing concern in cardiac surgery, with a still relevant incidence and with a considerable impact on in-hospital mortality and also on mid- and long-term survival. The permanent high impact of this complication is partially related to the increasing proportion of patients at high-risk for infection, as well as to the many patient and surgical risk factors involved in the pathogenesis of DSWI. The prophylactic antibiotic therapy is one of the most important tools in the prevention of DSWI. However, the choice of antibiotic, the dose, the duration, the adequate levels in serum and tissue, and the timing of antimicrobial prophylaxis are still controversial. The treatment of DSWI ranges from surgical revision with primary closure to surgical revision with open dressings or closed irrigation, from reconstruction with soft tissue flaps to negative pressure wound therapy (NPWT). However, to date, there have been no accepted recommendations regarding the best management of DSWI. Emerging evidence in the literature has validated the efficacy and safety of NPWT either as a single-line therapy, or as a "bridge" prior to final surgical closure. In conclusion, the careful control of patient and surgical risk factors - when possible, the proper antimicrobial prophylaxis, and the choice of validated techniques of treatment could contribute to keep DSWIs at a minimal rate.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.