ArticlePeerJ2015
Effect of shampoo, conditioner and permanent waving on the molecular structure of human hair.
Article in PeerJ, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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Who cites it
15 citing papers in PubMed, 51 citations in OpenAlex.
- Achieving Highly Efficient Repeatable Hair Perming by Bunte Salt-Thiol Exchange Reaction.ACS omega · 2026Article
- Online Survey on Perceptions and Practices of Hair Oiling Among Diverse Demographics in the Southern States of India.Indian dermatology online journal · 2026Article
- Article
- Application of Alkyl Polyglucosides as Components of the Extraction Medium in the Preparation of a Shampoo Cosmetic Formulation Containing Substances Isolated from Red Grape Pomace.Molecules (Basel, Switzerland) · 2025Article
- Alterations promoted by acid straightening and/or bleaching in hair microstructures.Journal of applied crystallography · 2023Article
- Mechanisms of impairment in hair and scalp induced by hair dyeing and perming and potential interventions.Frontiers in medicine · 2023Review
- Knowledge of Traction Alopecia and Hair Care Practices among Adolescents in Keffi, North-Central Nigeria.Skin appendage disorders · 2022Article
- Review
- Automated analysis of scanning electron microscopic images for assessment of hair surface damage.Royal Society open science · 2020Article
- Conformation changes in human hair keratin observed using confocal Raman spectroscopy after active ingredient application.International journal of cosmetic science · 2019Review
- Hair Proteome Variation at Different Body Locations on Genetically Variant Peptide Detection for Protein-Based Human Identification.Scientific reports · 2019Article
- Giant axonal neuropathy alters the structure of keratin intermediate filaments in human hair.Journal of the Royal Society, Interface · 2017Article
- The Molecular Structure of Human Red Blood Cell Membranes from Highly Oriented, Solid Supported Multi-Lamellar Membranes.Scientific reports · 2017Article
- Article
- A Study on Scalp Hair Health and Hair Care Practices among Malaysian Medical Students.International journal of trichologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The hair is a filamentous biomaterial consisting of the cuticle, the cortex and the medulla, all held together by the cell membrane complex. The cortex mostly consists of helical keratin proteins that spiral together to form coiled-coil dimers, intermediate filaments, micro-fibrils and macro-fibrils. We used X-ray diffraction to study hair structure on the molecular level, at length scales between ∼3-90 Å, in hopes of developing a diagnostic method for diseases affecting hair structure allowing for fast and noninvasive screening. However, such an approach can only be successful if common hair treatments do not affect molecular hair structure. We found that a single use of shampoo and conditioner has no effect on packing of keratin molecules, structure of the intermediate filaments or internal lipid composition of the membrane complex. Permanent waving treatments are known to break and reform disulfide linkages in the hair. Single application of a perming product was found to deeply penetrate the hair and reduce the number of keratin coiled-coils and change the structure of the intermediate filaments. Signals related to the coiled-coil structure of the α-keratin molecules at 5 and 9.5 Å were found to be decreased while a signal associated with the organization of the intermediate filaments at 47 Å was significantly elevated in permed hair. Both these observations are related to breaking of the bonds between two coiled-coil keratin dimers.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.