Evidence map›Paper›PMID 26557338›Full record

ReviewAudiology research2012

Characteristics of multiple sclerosis patient stance control disorders, measured by means of posturography and related to brainstem lesions.

Dario Alpini, Federica Di Berardino, Valentina Mattei, Domenico Caputo, Peter Schalek, Antonio Cesarani

Abstract readReview
In one paragraph

Review in Audiology research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Postural Control in Relapsing-Remitting Multiple Sclerosis.International archives of otorhinolaryngology · 2022
    Article
  3. Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Dario AlpiniScientific Institute S. Maria Nascente, Don Carlo Cnocchi Foundation, Milan, Italy;
Federica Di BerardinoDipartimento di Scienze Chirurgiche Specialistiche, Università degli Studi di Milano, Milan, Italy;
Valentina MatteiScientific Institute S. Maria Nascente, Don Carlo Cnocchi Foundation, Milan, Italy;
Domenico CaputoScientific Institute S. Maria Nascente, Don Carlo Cnocchi Foundation, Milan, Italy;
Peter SchalekENT Institute III Medical Faculty Charles University, Prague, Czech Republik;
Antonio CesaraniDipartimento di Scienze Chirurgiche Specialistiche, Università degli Studi di Milano, Milan, Italy; ; Audiology Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Balance disorders are commonly observed during the course of multiple sclerosis (MS). The aim of this study is to report characteristics of MS patient stance control disorders, measured by means of posturography and related to the brainstem lesions. Thirty-eight patients affected by MS, mildly to moderately disable according to Kurtzke's Expanded Disability Status Scale, underwent a complete clinical neurological and vestibular evaluation and brain MRI scanning. All patients were then tested on a static posturography platform (Tetrax, Israel) in four conditions: eyes open and eyes closed standing on a firm surface and on a foam pad. Clinical and/or magnetic resonance imaging evidence of brainstem involvement was observed in 55.3% of patients. When brainstem lesion was detected, Fourier analysis showed a typical pattern characterized by inversion of the 0-0.1 Hz and 0.1-0.25 Hz frequency bands. In conclusion, MS leads to pervasive postural disturbances in the majority of subjects, including the visuo-vestibular loops and proprioception involving vestibulo-spinal pathways in at least 55.3% of patients. Our results may also suggest the presence of Fourier inversion in patients with brainstem lesions.

Indexed as

magnetic resonance imagingmultiple sclerosisposturographyvestibulo-spinal reflex.

Identifiers

PMID26557338
PMCPMC4630951

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.