ArticleOncotarget2016
Clinical significance of accurate identification of lymph node status in distant metastatic gastric cancer.
Article in Oncotarget, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 19 citations in OpenAlex.
- Co-expression pattern of SLC transporter genes associated with the immune landscape and clinical outcomes in gastric cancer.Journal of cellular and molecular medicine · 2023Article
- Evaluation of Four Lymph Node Classifications for the Prediction of Survival in Hilar Cholangiocarcinoma.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2022Article
- A Predictive Nomogram for Early Mortality in Stage IV Gastric Cancer.Medical science monitor : international medical journal of experimental and clinical research · 2020Article
- Gastric Cancer Peritoneal Carcinomatosis Risk Score.Annals of surgical oncology · 2020Article
- Proposal of a Nomogram for Predicting Survival in Patients with Siewert Type II Adenocarcinoma of the Esophagogastric Junction After Preoperative Radiation.Annals of surgical oncology · 2019Article
- Effect of lymph nodes count in node-positive gastric cancer.Journal of Cancer · 2019Article
- The association of the lymph node ratio and serum carbohydrate antigen 19-9 with early recurrence after curative gastrectomy for gastric cancer.Surgery today · 2018Article
- Gene expression profiles for a prognostic immunoscore in gastric cancer.The British journal of surgery · 2018Article
- Negative lymph node count is a significant prognostic factor in patient with stage IV gastric cancer after palliative gastrectomy.Oncotarget · 2017Article
- Lymph node status as a prognostic factor after palliative resection of primary tumor for patients with metastatic colorectal cancer.Oncotarget · 2017Article
- The prognostic value of negative lymph node count for patients with gastric cancer who received preoperative radiotherapy.Oncotarget · 2017Article
- Age-specific effects on the prognosis after surgery for gastric cancer: A SEER population-based analysis.Oncotarget · 2016Article
- The prognostic value of lymph nodes count on survival of patients with node-negative gastric cancer.Oncotarget · 2016Article
- Increased number of negative lymph nodes is associated with improved survival outcome in node positive gastric cancer following radical gastrectomy.Oncotarget · 2016Article
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe clinical consequences of accurately identifying lymph node (LN) status in distant metastatic gastric cancer (DMGC) are unclear. We aimed to determine the prognostic significance of N stage, positive LN (PLN) count, and the positive LN ratio (LNR). We also retrospectively compared survival outcomes of DMGC patients stratified by LN dissection (LND).
resultsLND was performed in 1593 patients. The CSS was significantly different between groups divided according to N stage, PLN, and LNR in DMGC patients who underwent LND. Lower LNR was an independent predictor of longer survival in all kinds of patients cohorts, whereas PLN was not such a predictor. PLN count correlated with LND number and LNR. No correlation existed between LNR and LND number. Undergoing LND and having a higher number of dissected LNs were associated with superior CSS. MATERIALS AND
methodsData from 1889 DMGC patients treated between 2004 and 2009, and documented in the Surveillance, Epidemiology, and End Results (SEER) registry, were reviewed. Pearson's correlation coefficient and the Chi-square test were used to study the relationships between LND number, PLN count, N stage, and the LNR. Cancer-specific survival (CSS) was evaluated using Kaplan-Meier analysis, with the log-rank test performed for univariate analysis (UVA) and the Cox proportional hazards model employed for multivariate analysis (MVA).
conclusionLN metastatic variables play important roles in the prognostic evaluation and treatment decisions of DMGC patients. Accurate identification of LN status in DMGC patients is critical. LND performance is associated with increased survival and has clinical practicability.
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