Evidence map›Paper›PMID 26556622›Full record

ArticleIntensive care medicine2016

Prospective study of a proactive palliative care rounding intervention in a medical ICU.

Nicholas Braus, Toby C Campbell, Kristine L Kwekkeboom, Susan Ferguson, Carrie Harvey, Anna E Krupp, Tara Lohmeier, Michael D Repplinger, Ryan P Westergaard, Elizabeth A Jacobs and 2 more

3 registry-linked trialsOpen access · greenAbstract read
In one paragraph

Article in Intensive care medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 35 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 5 pooled it
6.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03263143 nacompletednot on this mapstarted 2017, after this paper: background citation

Early Palliative Care in the Medical Intensive Care Unit

TypeinterventionalSponsorWashington University School of MedicineRan2017 to 2018Enrolled242ConditionsPalliative CareArmsPalliative Care
NCT03287323 naunknown statusnot on this mapstarted 2017, after this paper: background citation

The Influence of a Proactive Palliative Care Intervention on Family Satisfaction and Biopsychosocial Problem-related Distress of Patients in a Surgical Intensive Care Unit: A Prospective Single-center Interventional Study

TypeinterventionalSponsorJohannes Gutenberg University MainzRan2017 to 2021Enrolled200ConditionsPalliative CareArmsProactive Palliative Care
NCT06574672 narecruitingnot on this mapstarted 2024, after this paper: background citation

Impact of an Embedded Palliative Care and Hospice Practitioner in the Medical ICU

TypeinterventionalSponsorWashington University School of MedicineRan2024 to 2027Enrolled2,600ConditionsCritical Illness, End of Life, Quality of LifeArmsEmbedded Hospice and Palliative Care Practitioner, Embedded Hospice and Palliative Care Practitioner (Group Effect), None (Historical)
3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 5 syntheses or guidelines pooled it, 83 citations in OpenAlex.

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  10. Neurology and physician-assisted suicide: glossary of definitions and terminology.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
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  19. Exploratory Study of Palliative Care Utilization and Medical Expense for Inpatients at the End-of-Life.International journal of environmental research and public health · 2022
    Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Nicholas BrausDepartment of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.
Toby C CampbellDivision of Hematology and Oncology, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.
Kristine L KwekkeboomSchool of Nursing, University of Wisconsin, Madison, WI, USA.
Susan FergusonDepartment of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.
Carrie HarveyDepartment of Anesthesiology, University of Michigan, Ann Arbor, MI, USA.
Anna E KruppSchool of Nursing, University of Wisconsin, Madison, WI, USA.
Tara LohmeierDepartment of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.
Michael D RepplingerDepartment of Emergency Medicine, University of Wisconsin School of Medicine and Public Health, Madison, USA.
Ryan P WestergaardDivision of Infectious Diseases, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, USA.
Elizabeth A JacobsDivision of General Internal Medicine, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, USA.
Kate Ford RobertsUniversity of Wisconsin Hospital and Clinics, Madison, WI, USA.
William J EhlenbachDivisions of Pulmonary and Critical Care Medicine, Allergy and Geriatrics and Gerontology, Department of Medicine, University of Wisconsin School of Medicine and Public Health, 5230 Medical Foundation Centennial Building, 1685 Highland Avenue, mail code 2281, Madison, WI, 53705-2281, USA. wjehlen@medicine.wisc.edu.ORCID http://orcid.org/0000-0002-2864-5543
University of Wisconsin–Madison · USUniversity of Michigan · USUW Health University Hospital · US

Funding

UW COMPREHENSIVE CANCER CENTER SUPPORTP30CA014520 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI AMY TRENTHAM-DIETZ · 1985 to 2026
$142.6M
Institutional Clinical and Translational Science AwardUL1TR000427 · NCATS · UNIVERSITY OF WISCONSIN-MADISON · PI DREZNER, MARC KENNETH · 2012 to 2016
$32.2M
Cognitive outcomes and neuropathology in older adults following critical illnessK23AG038352 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI EHLENBACH, WILLIAM JOSEPH · 2011 to 2015
$759k
NCATS NIH HHS UL1 TR000427NCATS NIH HHS UL1TR000427NCI NIH HHS P30 CA014520NIA NIH HHS K23 AG038352
6 · The paper itself

Abstract

purposeTo evaluate the effects of a palliative care intervention on clinical and family outcomes, and palliative care processes.

methodsProspective, before-and-after interventional study enrolling patients with high risk of mortality, morbidity, or unmet palliative care needs in a 24-bed academic intensive care unit (ICU). The intervention involved a palliative care clinician interacting with the ICU physicians on daily rounds for high-risk patients.

resultsOne hundred patients were enrolled in the usual care phase, and 103 patients were enrolled during the intervention phase. The adjusted likelihood of a family meeting in ICU was 63% higher (RR 1.63, 95% CI 1.14-2.07, p = 0.01), and time to family meeting was 41% shorter (95% CI 52-28% shorter, p < 0.001). Adjusted ICU length of stay (LOS) was not significantly different between the two groups (6% shorter, 95% CI 16% shorter to 4% longer, p = 0.22). Among those who died in the hospital, ICU LOS was 19% shorter in the intervention (95% CI 33-1% shorter, p = 0.043). Adjusted hospital LOS was 26% shorter (95% CI 31-20% shorter, p < 0.001) with the intervention. Post-traumatic stress disorder (PTSD) symptoms were present in 9.1% of family respondents during the intervention versus 20.7% prior to the intervention (p = 0.09). Mortality, family depressive symptoms, family satisfaction and quality of death and dying did not significantly differ between groups.

conclusionsProactive palliative care involvement on ICU rounds for high-risk patients was associated with more and earlier ICU family meetings and shorter hospital LOS. We did not identify differences in family satisfaction, family psychological symptoms, or family-rated quality of dying, but had limited power to detect such differences.

Indexed as

Professional-Family RelationsAgedAged, 80 and overDecision MakingFamilyFemaleHumansIntensive Care UnitsLength of StayLogistic ModelsMaleMiddle AgedPalliative CarePatient Care TeamProspective StudiesTerminal CareCommunicationEnd-of-life careFamily ICU syndromeFamily meetingsICU decision-makingPalliative care

Identifiers

PMID26556622
PMCPMC4945103
OpenAlexW2259680946

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.