Evidence map›Paper›PMID 26556561›Full record

ArticleJournal of biophotonics2016

Transmission in near-infrared optical windows for deep brain imaging.

Lingyan Shi, Laura A Sordillo, Adrián Rodríguez-Contreras, Robert Alfano

Open access · greenAbstract read
In one paragraph

Article in Journal of biophotonics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers.

0numbers the graph read from it
0cells of the map it votes in
75citing papers in PubMed
22.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

75 citing papers in PubMed, 332 citations in OpenAlex.

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  8. Life beyond labels.Nature methods · 2025
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15 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Lingyan ShiInstitute for Ultrafast Spectroscopy and Lasers, Department of Physics, the City College of the City University of New York, 160 Convent Avenue, New York, NY 10031, USA. lshi365@gmail.com.
Laura A SordilloInstitute for Ultrafast Spectroscopy and Lasers, Department of Physics, the City College of the City University of New York, 160 Convent Avenue, New York, NY 10031, USA.
Adrián Rodríguez-ContrerasInstitute for Ultrafast Spectroscopy and Lasers, Department of Physics, the City College of the City University of New York, 160 Convent Avenue, New York, NY 10031, USA.
Robert AlfanoInstitute for Ultrafast Spectroscopy and Lasers, Department of Physics, the City College of the City University of New York, 160 Convent Avenue, New York, NY 10031, USA.
City College of New York · USCity University of New York · US

Funding

TNC FUNCTION IN APOPTOTIC ANTIGEN DRIVEN AUTOIMMUNITYG12RR003060 · NCRR · CITY COLLEGE OF NEW YORK · PI GUYDEN, JERRY · 1985 to 2011
$26.1M
Cellular/Molecular Basis of Development: Research CenterG12MD007603 · NIMHD · CITY COLLEGE OF NEW YORK · PI PEZZANO, MARK · 2012 to 2017
$11.5M
Neuronal ensembles during development of tonotopic maps in the auditory systemsSC1HD068129 · NICHD · CITY COLLEGE OF NEW YORK · PI RODRIGUEZ-CONTRERAS, ADRIAN · 2010 to 2014
$1.1M
Neuronal ensembles during development of tonotopic maps in the auditory systemSC1DC015907 · NIDCD · CITY COLLEGE OF NEW YORK · PI RODRIGUEZ-CONTRERAS, ADRIAN · 2016 to 2018
$706k
NCRR NIH HHS 2G12RR003060-26A1NCRR NIH HHS G12 RR003060NICHD NIH HHS 5SC1HD068129NICHD NIH HHS SC1 HD068129NIDCD NIH HHS SC1 DC015907NIMHD NIH HHS G12 MD007603
6 · The paper itself

Abstract

Near-infrared (NIR) radiation has been employed using one- and two-photon excitation of fluorescence imaging at wavelengths 650-950 nm (optical window I) for deep brain imaging; however, longer wavelengths in NIR have been overlooked due to a lack of suitable NIR-low band gap semiconductor imaging detectors and/or femtosecond laser sources. This research introduces three new optical windows in NIR and demonstrates their potential for deep brain tissue imaging. The transmittances are measured in rat brain tissue in the second (II, 1,100-1,350 nm), third (III, 1,600-1,870 nm), and fourth (IV, centered at 2,200 nm) NIR optical tissue windows. The relationship between transmission and tissue thickness is measured and compared with the theory. Due to a reduction in scattering and minimal absorption, window III is shown to be the best for deep brain imaging, and windows II and IV show similar but better potential for deep imaging than window I.

Indexed as

Infrared RaysAnimalsBrainOptical ImagingOptical PhenomenaRatsScattering, Radiationdeep brain imaginggolden optical tissue windownear-infraredtotal attenuation lengthtransmittance

Identifiers

PMID26556561
PMCPMC4827444
OpenAlexW2155724387

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.