Evidence map›Paper›PMID 26556547›Full record

ArticleArchives of oral biology2016

Occurrence and serotype distribution of Aggregatibacter actinomycetemcomitans in subjects without periodontitis in Turkey.

Başak Doğan, Jason Chen, Sinem Yıldız Çiftlikli, Jonathan Huang, Tanju Kadir, Anıl Kınacı Alnıak, Casey Chen

Open access · greenAbstract read
In one paragraph

Article in Archives of oral biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Fimbriae potentiateCurrent research in microbial sciences · 2026
    Review
  2. Article
  3. Article
  4. Frontiers in oral health · 2022
    Article
  5. Aggregatibacter actinomycetemcomitans: From Basic to Advanced Research.Advances in experimental medicine and biology · 2022
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Başak DoğanDepartment of Periodontology, Faculty of Dentistry, Marmara University, Istanbul, Turkey.
Jason ChenDivision of Periodontology, Diagnostic Sciences and Dental Hygiene, Ostrow School of Dentistry, University of Southern California, USA.
Sinem Yıldız ÇiftlikliDepartment of Periodontology, Faculty of Dentistry, Marmara University, Istanbul, Turkey.
Jonathan HuangDivision of Periodontology, Diagnostic Sciences and Dental Hygiene, Ostrow School of Dentistry, University of Southern California, USA.
Tanju KadirDepartment of Microbiology, Faculty of Dentistry, Marmara University, Istanbul, Turkey.
Anıl Kınacı AlnıakDepartment of Periodontology, Faculty of Dentistry, Marmara University, Istanbul, Turkey.
Casey ChenDivision of Periodontology, Diagnostic Sciences and Dental Hygiene, Ostrow School of Dentistry, University of Southern California, USA. Electronic address: ccchen@usc.edu.
Marmara University · TRUniversity of Southern California · US

Funding

Novel clone-specific virulence determinants of A. actinomycetemcomitansR01DE012212 · NIDCR · UNIVERSITY OF SOUTHERN CALIFORNIA · PI CHEN, CASEY · 1999 to 2016
$5.0M
NIDCR NIH HHS R01 DE012212
6 · The paper itself

Abstract

objectiveTo determine the occurrence and serotype distribution of Aggregatibacter actinomycetemcomitans in subjects without periodontitis.

designSystemically healthy dental students without periodontitis (n=94), who had not used antibiotics within the last 3 months or received any form of periodontal therapy within the last 6 months, were included in the study. Pooled subgingival microbiological samples were collected from 4 first molars and 4 central incisors in each subject using sterile paper points. All samples were tested for the presence and the serotype of A. actinomycetemcomitans through PCR analysis of the 16S rRNA genes and the serotype-specific gene clusters in the DNA extracted from the samples.

resultsOf the 94 samples that were tested, 43 (46%) were positive for A. actinomycetemcomitans. No statistically significant differences in clinical parameters were found between subgingival sites with or without detectable A. actinomycetemcomitans (t-test, P>0.01). Among the 43 A. actinomycetemcomitans-positive samples, the serotype was identified in 21 samples. Fifteen were positive for A. actinomycetemcomitans serotype a, 1 for serotype b, 1 for serotype c, and 4 for serotype f, while serotypes d and e were not detected.

conclusionA. actinomycetemcomitans serotype a is the most commonly found serotype among Turkish dental students without periodontitis.

Indexed as

AdultAggregatibacter actinomycetemcomitansFemaleHumansMaleMouthPolymerase Chain ReactionSerotypingTurkeyPCRPeriodontitisSerotypeVirulence

Identifiers

PMID26556547
PMCPMC4679624
OpenAlexW2187453269

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.