ArticleBioinformatics (Oxford, England)2016
SpectralTDF: transition densities of diffusion processes with time-varying selection parameters, mutation rates and effective population sizes.
Article in Bioinformatics (Oxford, England), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed.
- diplo-locus: a lightweight toolkit for inference and simulation of time-series genetic data under general diploid selection.G3 (Bethesda, Md.) · 2025Article
- diplo-locus: A lightweight toolkit for inference and simulation of time-series genetic data under general diploid selection.bioRxiv : the preprint server for biology · 2025Article
- Article
- A Path Integral Approach for Allele Frequency Dynamics Under Polygenic Selection.bioRxiv : the preprint server for biology · 2024Article
- Article
- EWF: simulating exact paths of the Wright-Fisher diffusion.Bioinformatics (Oxford, England) · 2023Article
- Allele Age Under Non-Classical Assumptions is Clarified by an Exact Computational Markov Chain Approach.Scientific reports · 2017Article
- Statistical Inference in the Wright-Fisher Model Using Allele Frequency Data.Systematic biology · 2017Review
- The Effects of Population Size Histories on Estimates of Selection Coefficients from Time-Series Genetic Data.Molecular biology and evolution · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
motivationIn the Wright-Fisher diffusion, the transition density function describes the time evolution of the population-wide frequency of an allele. This function has several practical applications in population genetics and computing it for biologically realistic scenarios with selection and demography is an important problem.
resultsWe develop an efficient method for finding a spectral representation of the transition density function for a general model where the effective population size, selection coefficients and mutation parameters vary over time in a piecewise constant manner. AVAILABILITY AND IMPLEMENTATION: The method, called SpectralTDF, is available at https://sourceforge.net/projects/spectraltdf/ CONTACT: yss@berkeley.edu SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.