Evidence map›Paper›PMID 26556364›Full record

ReviewPharmaceutics2015

Microneedle Coating Techniques for Transdermal Drug Delivery.

Rita Haj-Ahmad, Hashim Khan, Muhammad Sohail Arshad, Manoochehr Rasekh, Amjad Hussain, Susannah Walsh, Xiang Li, Ming-Wei Chang, Zeeshan Ahmad

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Pharmaceutics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 172 citations in OpenAlex.

  1. Bioelectronic Considerations in Biomedical Microneedles.Small (Weinheim an der Bergstrasse, Germany) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 3 countries.

Rita Haj-AhmadSchool of Pharmacy, De Montfort University, Leicester LE1 9BH, UK. rita.haj-ahmad@sunderland.ac.uk.
Hashim KhanSchool of Pharmacy, De Montfort University, Leicester LE1 9BH, UK. hashimkhan15@googlemail.com.
Muhammad Sohail ArshadSchool of Pharmacy, De Montfort University, Leicester LE1 9BH, UK. sohail_arshad79@yahoo.com.
Manoochehr RasekhSchool of Pharmacy, De Montfort University, Leicester LE1 9BH, UK. m.rasekh@alumni.ucl.ac.uk.
Amjad HussainSchool of Pharmacy, De Montfort University, Leicester LE1 9BH, UK. amjad_husein@hotmail.com.
Susannah WalshSchool of Pharmacy, De Montfort University, Leicester LE1 9BH, UK. SWalsh@dmu.ac.uk.
Xiang LiState Key Laboratory of Silicon Materials, School of Materials Science and Engineering, Zhejiang University, Hangzhou 310027, China. xiang.li@zju.edu.cn.
Ming-Wei ChangCollege of Biomedical Engineering and Instrument Science, Zhejiang University, Hangzhou 310027, China. mwchang@zju.edu.cn.
Zeeshan AhmadSchool of Pharmacy, De Montfort University, Leicester LE1 9BH, UK. zahmad@dmu.ac.uk.
De Montfort University · GBBahauddin Zakariya University · PKUniversity of the Punjab · PKZhejiang University · CNZhejiang University of Science and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Drug administration via the transdermal route is an evolving field that provides an alternative to oral and parenteral routes of therapy. Several microneedle (MN) based approaches have been developed. Among these, coated MNs (typically where drug is deposited on MN tips) are a minimally invasive method to deliver drugs and vaccines through the skin. In this review, we describe several processes to coat MNs. These include dip coating, gas jet drying, spray coating, electrohydrodynamic atomisation (EHDA) based processes and piezoelectric inkjet printing. Examples of process mechanisms, conditions and tested formulations are provided. As these processes are independent techniques, modifications to facilitate MN coatings are elucidated. In summary, the outcomes and potential value for each technique provides opportunities to overcome formulation or dosage form limitations. While there are significant developments in solid degradable MNs, coated MNs (through the various techniques described) have potential to be utilized in personalized drug delivery via controlled deposition onto MN templates.

Indexed as

coating processcoatingsdrug deliveryfilmsmicroneedlesparticles

Identifiers

PMID26556364
PMCPMC4695830
OpenAlexW2161108328

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.