ReviewViruses2015
The Impact of Wolbachia on Virus Infection in Mosquitoes.
Review in Viruses, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 77 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Applying Wolbachia to Eliminate Dengue (AWED): A Non-blinded Cluster Randomised Controlled Trial to Assess the Efficacy of Wolbachia-infected Mosquito Deployments to Reduce Dengue Incidence in Yogyakarta, Indonesia
World Mosquito Program - Colombia (WMP-COLOMBIA): The Impact of City-wide Deployment of Wolbachia-infected Mosquitoes on Arboviral Disease Incidence in Medellin and Bello, Colombia
Who cites it
77 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Wolbachia-carrying Aedes mosquitoes for preventing dengue infection.The Cochrane database of systematic reviews · 2024Pooled it
- CircRNA-encoded protein fine-tunes ROS homeostasis and engages conserved JAK-STAT antiviral defenses inJournal of virology · 2026Article
- Article
- The inhibition mechanism ofFrontiers in microbiology · 2026Review
- Review
- Molecular evidence of Wolbachia and Orthoflavivirus infection in field-collected mosquitoes in three provinces of Türkiye.Tropical medicine & international health : TM & IH · 2025Article
- Detection of a sympatric cryptic species mimicking Aedes albopictus (Diptera: Culicidae) in dengue and Chikungunya endemic forest villages of Tripura, India, posing a daunting challenge for vector research.Scientific reports · 2025Article
- Malagasy flea microbiota results from a combination of vertically transmitted and environmentally acquired microbes.Scientific reports · 2025Article
- Potential mechanisms implied in tick infection by arboviruses and their transmission to vertebrate hosts.Integrative zoology · 2025Review
- Review
- Nested patterns of commensals and endosymbionts in microbial communities of mosquito vectors.BMC microbiology · 2024Article
- Wolbachia infection in natural mosquito populations from Argentina.Parasitology research · 2024Article
- Vector competence of Aedes albopictus field populations from Reunion Island exposed to local epidemic dengue viruses.PloS one · 2024Article
- Highly Reduced Complementary Genomes of Dual Bacterial Symbionts in the Mulberry Psyllid Anomoneura mori.Microbes and environments · 2024Article
- A comprehensive review ofFrontiers in immunology · 2024Review
- Use of Antibiotics to Eliminate Wolbachia from Mosquitoes and Cell Culture.Methods in molecular biology (Clifton, N.J.) · 2024Article
- RANDOMIZATION INFERENCE FOR CLUSTER-RANDOMIZED TEST-NEGATIVE DESIGNS WITH APPLICATION TO DENGUE STUDIES: UNBIASED ESTIMATION, PARTIAL COMPLIANCE, AND STEPPED-WEDGE DESIGN.The annals of applied statistics · 2023Article
- Differences in gene expression in field populations of Wolbachia-infected Aedes aegypti mosquitoes with varying release histories in northern Australia.PLoS neglected tropical diseases · 2023Article
- Article
- The interplay between vector microbial community and pathogen transmission on the invasive Asian tiger mosquito,Frontiers in microbiology · 2023Review
17 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mosquito-borne viruses such as dengue, West Nile and chikungunya viruses cause significant morbidity and mortality in human populations. Since current methods are not sufficient to control disease occurrence, novel methods to control transmission of arboviruses would be beneficial. Recent studies have shown that virus infection and transmission in insects can be impeded by co-infection with the bacterium Wolbachia pipientis. Wolbachia is a maternally inherited endosymbiont that is commonly found in insects, including a number of mosquito vector species. In Drosophila, Wolbachia mediates antiviral protection against a broad range of RNA viruses. This discovery pointed to a potential strategy to interfere with mosquito transmission of arboviruses by artificially infecting mosquitoes with Wolbachia. This review outlines research on the prevalence of Wolbachia in mosquito vector species and the impact of antiviral effects in both naturally and artificially Wolbachia-infected mosquitoes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.