ArticleMolecules (Basel, Switzerland)2015
Production of Nanoemulsions from Palm-Based Tocotrienol Rich Fraction by Microfluidization.
Article in Molecules (Basel, Switzerland), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Silver-LoadedMarine drugs · 2026Article
- High-Load Amino Acid Nanoemulsion: Physicochemical Optimization and Dermal Bioactivity.ACS omega · 2026Article
- Locally Acting Budesonide-Loaded Solid Self-Microemulsifying Drug Delivery Systems (SMEDDS) for Distal Ulcerative Colitis.International journal of nanomedicine · 2024Article
- Citronella essential oil-based nanoemulsion as a post-emergence natural herbicide.Scientific reports · 2023Article
- Curcumin: Overview of Extraction Methods, Health Benefits, and Encapsulation and Delivery Using Microemulsions and Nanoemulsions.International journal of molecular sciences · 2023Review
- Boosting Tadalafil Bioavailability via Sono-Assisted Nano-Emulsion-Based Oral Jellies: Box-Behnken Optimization and Assessment.Pharmaceutics · 2022Article
- Tadalafil-Loaded Self-Nanoemulsifying Chewable Tablets for Improved Bioavailability: Design, In Vitro, and In Vivo Testing.Pharmaceutics · 2022Article
- Eco-friendly pesticide based on peppermint oil nanoemulsion: preparation, physicochemical properties, and its aphicidal activity against cotton aphid.Environmental science and pollution research international · 2020Article
- Techniques for Formulation of Nanoemulsion Drug Delivery System: A Review.Preventive nutrition and food science · 2019Review
- Use of Lipid Nanocarriers to Improve Oral Delivery of Vitamins.Nutrients · 2019Review
- Challenges and Opportunities of Nanotechnology as Delivery Platform for Tocotrienols in Cancer Therapy.Frontiers in pharmacology · 2018Review
- Microfluidization trends in the development of nanodelivery systems and applications in chronic disease treatments.International journal of nanomedicine · 2018Review
Corrections and comments
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Authors and funding
5 authors.
Funding
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Abstract
In the present study, tocotrienol rich fraction (TRF) nanoemulsions were produced as an alternative approach to improve solubility and absorption of tocotrienols. In the present study, droplet size obtained after 10 cycles of homogenization with increasing pressure was found to decrease from 120 to 65.1 nm. Nanoemulsions stabilized with Tween series alone or emulsifier blend Brij 35:Span 80 (0.6:0.4 w/w) homogenized at 25,000 psi and 10 cycles, produced droplet size less than 100 nm and a narrow size distribution with a polydispersity index (PDI) value lower than 0.2. However blend of Tween series with Span 80 produced nanoemulsions with droplet size larger than 200 nm. This work has also demonstrated the amount of tocols losses in TRF nanoemulsion stabilized Tweens alone or emulsifier blend Brij 35:Span 80 (0.6:0.4 w/w) ranged between 3%-25%. This can be attributed to the interfacial film formed surrounding the droplets exhibited different level of oxidative stability against heat and free radicals created during high pressure emulsification.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.