ArticleMalaria journal2015
Frequency and distribution of mixed Plasmodium falciparum-vivax infections in French Guiana between 2000 and 2008.
Article in Malaria journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 16 citations in OpenAlex.
- First field evaluation of novel LDH- and HRP2-based rapid tests for Plasmodium vivax and Plasmodium falciparum malaria diagnosis.PLoS neglected tropical diseases · 2025Article
- Comparison of SD Bioline Malaria Ag Pf/Pan and Acro Malaria P.f./P.v./Pan with Microscopy and Real Time PCR for the Diagnosis of HumanDiagnostics (Basel, Switzerland) · 2024Article
- Assessment of a Commercial Real-Time PCR Assay (Vitassay qPCR Malaria 5 Test) to Detect Human Malaria Infection in Travelers Returning to France.Diagnostics (Basel, Switzerland) · 2022Article
- Comparative Assessment of the Sensitivity of Ten Commercial Rapid Diagnostic Test Kits for the Detection ofDiagnostics (Basel, Switzerland) · 2022Article
- Contributing to Elimination of Cross-Border Malaria Through a Standardized Solution for Case Surveillance, Data Sharing, and Data Interpretation: Development of a Cross-Border Monitoring System.JMIR public health and surveillance · 2020Article
- The enigmatic mechanisms by which Plasmodium vivax infects Duffy-negative individuals.PLoS pathogens · 2020Review
- Plasmodium genomics: an approach for learning about and ending human malaria.Parasitology research · 2019Review
- Spatiotemporal Clustering Analysis of Malaria Infection in Pakistan.International journal of environmental research and public health · 2018Article
- Decreased endemic malaria in Suriname: moving towards elimination.Malaria journal · 2018Article
- Facilitation through altered resource availability in a mixed-species rodent malaria infection.Ecology letters · 2016Article
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Authors and funding
11 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe two main plasmodial species in French Guiana are Plasmodium vivax and Plasmodium falciparum whose respective prevalence influences the frequency of mixed plasmodial infections. The accuracy of their diagnosis is influenced by the sensitivity of the method used, whereas neither microscopy nor rapid diagnostic tests allow a satisfactory evaluation of mixed plasmodial infections.
methodsIn the present study, the frequency of mixed infections in different part of French Guiana was determined using real time PCR, a sensitive and specific technique.
resultsFrom 400 cases of malaria initially diagnosed by microscopy, real time PCR showed that 10.75 % of the cases were mixed infections. Their prevalence varied considerably between geographical areas. The presence, in equivalent proportions, of the two plasmodial species in eastern French Guiana was associated with a much higher prevalence of mixed plasmodial infections than in western French Guiana, where the majority of the population was Duffy negative and thus resistant to vivax malaria.
conclusionClinicians must be more vigilant regarding mixed infections in co-endemic P. falciparum/P. vivax areas, in order to deliver optimal care for patients suffering from malaria. This may involve the use of rapid diagnostic tests capable of detecting mixed infections or low density single infections. This is important as French Guiana moves towards malaria elimination.
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