Evidence map›Paper›PMID 26555392›Full record

ArticleInsights into imaging2016

Lights and shadows of cardiac magnetic resonance imaging in acute myocarditis.

Antonio Esposito, Marco Francone, Riccardo Faletti, Maurizio Centonze, Filippo Cademartiri, Iacopo Carbone, Roberto De Rosa, Ernesto Di Cesare, Ludovico La Grutta, Guido Ligabue and 8 more

Open access · goldAbstract read
In one paragraph

Article in Insights into imaging, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 33 citations in OpenAlex.

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  14. Assessment of acute myocarditis by cardiac magnetic resonance imaging: Comparison of qualitative and quantitative analysis methods.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 12 institutions in 2 countries.

Antonio EspositoIRCCS Ospedale San Raffaele, Università Vita-Salute San Raffaele, Milan, Italy.
Marco FranconeDepartment of Radiological, Oncological and Pathological Sciences, Sapienza University of Rome, V.le Regina Elena 324, 00161, Rome, Italy. Marco.Francone@uniroma1.it.
Riccardo FalettiRadiologia Università Torino, Turin, Italy.
Maurizio CentonzeRadiologia OC S. Chiara Trento, Trento, Italy.
Filippo CademartiriDepartment of Radiology, Montreal Heart Institute, Universitè de Montreal, Montreal, Canada.
Iacopo CarboneDepartment of Radiological, Oncological and Pathological Sciences, Sapienza University of Rome, V.le Regina Elena 324, 00161, Rome, Italy.
Roberto De RosaASL Napoli 1, Naples, Italy.
Ernesto Di CesareDepartment of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.
Ludovico La GruttaPalermo University, Palermo, Italy.
Guido LigabueAzienda Ospedaliera-Universitaria Policlinico di Modena, Modena, Italy.
Luigi LovatoPoliclinico S. Orsola Bologna, Bologna, Italy.
Erica MaffeiDepartment of Radiology, Montreal Heart Institute, Universitè de Montreal, Montreal, Canada.
Riccardo MaranoUniversità Cattolica Roma, Rome, Italy.
Massimo MidiriPalermo University, Palermo, Italy.
Gianluca PontoneIRCCS Centro Cardiologico Monzino, Milan, Italy.
Luigi NataleUniversità Cattolica Roma, Rome, Italy.
Francesco De CobelliIRCCS Ospedale San Raffaele, Università Vita-Salute San Raffaele, Milan, Italy.
Working Group of the Italian College of Cardiac Radiology by SIRM
Università Cattolica del Sacro Cuore · ITUniversity of Palermo · ITCentro Cardiologico Monzino · ITIRCCS Ospedale San Raffaele · ITMontreal Heart Institute · CAOspedale Santa Chiara · ITPoliclinico di Modena · ITPoliclinico S.Orsola-Malpighi · ITUniversité de Montréal · CAUniversity of L'Aquila · ITUniversity of Turin · ITVita-Salute San Raffaele University · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

unlabelledCardiac magnetic resonance (CMR) is considered a primary tool for the diagnosis of acute myocarditis, due to its unique potential for non-invasive identification of the various hallmarks of the inflammatory response, with relevant impact on patient management and prognosis. Nonetheless, a marked variation in sensitivity and negative predictive value has been reported in the literature, reflecting the intrinsic drawbacks of current diagnostic criteria, which are based mainly on the use of conventional CMR pulse sequences. As a consequence, a negative exam cannot reliably exclude the diagnosis, especially in patients who do not present an infarct-like onset of disease. The introduction of new-generation mapping techniques further widened CMR potentials, allowing quantification of tissue changes and opening new avenues for non-invasive workup of patients with inflammatory myocardial disease. MAIN MESSAGES: • CMR sensitivity varies in AM, reflecting its clinical polymorphism and the intrinsic drawbacks of LLc. • Semiquantitative approaches such as EGEr or T2 ratio have limited accuracy in diffuse disease forms. • T1 mapping allows objective quantification of inflammation, with no need to normalize measurements. • A revised protocol including T2-STIR, T1 mapping and LGE could be hypothesized to improve sensitivity.

Indexed as

Acute myocarditisCardiac magnetic resonanceLake Louise criteriaT1 mapping

Identifiers

PMID26555392
PMCPMC4729715
OpenAlexW2131821739

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.