Evidence map›Paper›PMID 26555319›Full record

ArticleArthritis care & research2016

Link Between Foot Pain Severity and Prevalence of Depressive Symptoms.

Arunima Awale, Alyssa B Dufour, Patricia Katz, Hylton B Menz, Marian T Hannan

Open access · greenAbstract read
In one paragraph

Article in Arthritis care & research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.

  1. Pooled it
  2. Functional and quality of life outcomes after tibialis posterior transfer for foot drop from peroneal nerve injury.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 2 countries.

Arunima AwaleHebrew SeniorLife, Boston, Massachusetts.
Alyssa B DufourHebrew SeniorLife, Harvard Medical School, and Beth Israel Deaconess Medical Center, Boston, Massachusetts.
Patricia KatzUniversity of California, San Francisco.
Hylton B MenzLa Trobe University, Bundoora, Victoria, Australia.
Marian T HannanHebrew SeniorLife, Harvard Medical School, and Beth Israel Deaconess Medical Center, Boston, Massachusetts.
Beth Israel Deaconess Medical Center · USHarvard University · USHebrew SeniorLife · USLa Trobe University · AUUniversity of California, San Francisco · US

Funding

The Interplay of Sociodemographic and Genetic Factors in SLE Health DisparitiesP60AR053308 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI YELIN, EDWARD H · 2006 to 2016
$11.8M
Foot Disorders, Pain and Physical Disability in EldersR01AR047853 · NIAMS · HEBREW REHABILITATION CENTER FOR AGED · PI HANNAN, MARIAN T. · 2002 to 2012
$5.1M
THE FRAMINGHAM HEART STUDY-N01HC25195-268025195-268025195N01HC025195 · HC · TRUSTEES OF BOSTON UNIVERSITY · PI WOLF, PHILIP A · 2002 to 2006
–
NHLBI NIH HHS N01 HC025195NIAMS NIH HHS P60 AR053308NIAMS NIH HHS R01 AR047853
6 · The paper itself

Abstract

objectiveAssociations between pain and depression are well known, yet foot pain, common in populations, has been understudied. This cross-sectional study examined foot pain and severity of foot pain with depressive symptoms in adults.

methodsFramingham Foot Study (2002-2008) participants completed questionnaires that included questions about foot pain (yes/no; none, mild, moderate, or severe pain) and the Center for Epidemiologic Studies Depression Scale (scores ≥16 indicated depressive symptoms). Age and body mass index (BMI) were also assessed. Sex-specific logistic regression was used to calculate odds ratios (ORs) and 95% confidence intervals (95% CIs) for associations of foot pain with depressive symptoms, adjusting for age and BMI. In a subset, further models adjusted for leg pain, back pain, or other joint pain.

resultsOf 1,464 men and 1,857 women, the mean ± SD age was 66 ± 10 years. Depressive symptoms were reported in 21% of men and 27% of women. Compared to those with no foot pain and independent of age and BMI, both men and women with moderate foot pain had approximately a 2-fold increased odds of depressive symptoms (men with severe foot pain OR of 4 [95% CI 2.26-8.48], women with severe foot pain OR of 3 [95% CI 2.02-4.68]). Considering other pain regions attenuated ORs, but the pattern of results remained unchanged.

conclusionEven after we adjusted for age, BMI, and other regions of pain, those reporting worse foot pain were more likely to report depressive symptoms. These findings suggest that foot pain may be a part of a broader pain spectrum, with an impact beyond localized pain and discomfort.

Indexed as

AgedCohort StudiesCross-Sectional StudiesDepressionFemaleFootHumansMaleMiddle AgedOdds RatioPainPrevalenceSurveys and Questionnaires

Identifiers

PMID26555319
PMCPMC5607623
OpenAlexW2427788413

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.