Evidence map›Paper›PMID 26554869›Full record

Trial reportArthritis care & research2016

Link Between Positive Clinician-Conveyed Expectations of Treatment Effect and Pain Reduction in Knee Osteoarthritis, Mediated by Patient Self-Efficacy.

Grace Hsiao-Wei Lo, Ajay S Balasubramanyam, Andrea Barbo, Richard L Street, Maria E Suarez-Almazor

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Arthritis care & research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.1field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Grace Hsiao-Wei LoBaylor College of Medicine and the Michael E. DeBakey Veterans Affairs Medical Center, Houston, Texas.
Ajay S BalasubramanyamTexas A&M University Health Science Center, College Station.
Andrea BarboUniversity of Texas MD Anderson Cancer Center, Houston.
Richard L StreetTexas A&M University, College Station, and Baylor College of Medicine, Houston.
Maria E Suarez-AlmazorUniversity of Texas MD Anderson Cancer Center, Houston.
The University of Texas MD Anderson Cancer Center · USBaylor College of Medicine · USMichael E. DeBakey VA Medical Center · USTexas A&M Health Science Center · US

Funding

Outcomes Research in Rheumatic Diseases: A Mentoring ProgramK24AR053593 · NIAMS · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI SUAREZ-ALMAZOR, MARIA E · 2006 to 2015
$2.0M
Modifiable Risk Factors for Incident and Progressive Early Knee OsteoarthritisK23AR062127 · NIAMS · BAYLOR COLLEGE OF MEDICINE · PI LO, GRACE · 2012 to 2016
$676k
NIAMS NIH HHS K23 AR062127NIAMS NIH HHS K24 AR053593
6 · The paper itself

Abstract

objectiveA prior knee osteoarthritis (OA) trial found that provider-conveyed expectations for treatment success were associated with pain improvement. We hypothesized this relationship was mediated by patient self-efficacy, since expectations of improvement may enhance one's ability to control health behaviors, and therefore health. Our aim was to examine whether self-efficacy was a mediator of the relationship observed in this trial.

methodsA secondary analysis of a 3-arm (traditional acupuncture, sham acupuncture, and wait list) trial for knee OA was conducted. Those in the acupuncture groups were equally randomized to acupuncturists trained to communicate a high or neutral expectation of treatment success (e.g., using language conveying high or unclear likelihood that acupuncture would reduce knee pain). A modified Arthritis Self-Efficacy Questionnaire and the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) pain subscale were administered. Linear regression analyses were used to examine whether patient self-efficacy mediated the relationship between provider communication style and knee pain at 3 months.

resultsHigh-expectation provider communication was associated with patient self-efficacy, β coefficient of 0.14 (95% confidence interval [95% CI] 0.01, 0.28). Self-efficacy was associated with WOMAC pain, β coefficient of -9.29 (95% CI -11.11, -7.47), while controlling for the provider communication style. The indirect effect a × b of -1.36 for high versus neutral expectation (bootstrap 95% CI -2.80, -0.15; does not include 0), supports the conclusion that patient self-efficacy mediates the relationship between provider-communicated expectations of treatment effects and knee pain.

conclusionOur findings suggest that clinician-conveyed expectations can enhance the benefit of treatments targeting knee OA symptoms, mediated by improved patient self-efficacy.

Indexed as

Professional-Patient RelationsSelf EfficacyAcupuncture TherapyAgedFemaleHumansMaleMiddle AgedOsteoarthritis, KneePainPain Management

Identifiers

PMID26554869
PMCPMC4862923
OpenAlexW2464657283

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.