ArticleEpidemiology and infection2016
Disease burden of congenital cytomegalovirus infection at school entry age: study design, participation rate and birth prevalence.
Article in Epidemiology and infection, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed.
- Hearing and neurodevelopmental outcomes among children with congenital cytomegalovirus.International journal of pediatric otorhinolaryngology · 2025Article
- A Geographically Weighted Cost-effectiveness Analysis of Newborn Cytomegalovirus Screening.Open forum infectious diseases · 2024Article
- Estimates of congenital cytomegalovirus-attributable infant mortality in high-income countries: A review.Reviews in medical virology · 2024Review
- A High Risk of Missing Congenital Cytomegalovirus-Associated Hearing Loss through Newborn Hearing Screening in Japan.Journal of clinical medicine · 2021Article
- Economic assessments of the burden of congenital cytomegalovirus infection and the cost-effectiveness of prevention strategies.Seminars in perinatology · 2021Review
- Congenital CMV-Coded Diagnosis Among American Indian and Alaska Native Infants in the United States, 2000-2017.Journal of immigrant and minority health · 2020Article
- Short- and long-term impact of vaccination against cytomegalovirus: a modeling study.BMC medicine · 2020Article
- Valganciclovir Use Among Commercially and Medicaid-insured Infants With Congenital CMV Infection in the United States, 2009-2015.Clinical therapeutics · 2018Article
- Article
- Infectious reactivation of cytomegalovirus explaining age- and sex-specific patterns of seroprevalence.PLoS computational biology · 2017Article
- Congenital Cytomegalovirus Infection: Maternal-Child HLA-C, HLA-E, and HLA-G Affect Clinical Outcome.Frontiers in immunology · 2017Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Congenital cytomegalovirus infection (cCMV) may lead to symptoms at birth and long-term consequences. We present a nationwide, retrospective cohort study on the outcome of cCMV up to age 6 years. For this study we identified cCMV, using polymerase chain reaction, by analysing dried blood spots, which are taken shortly after birth for neonatal screening. The group of children with cCMV were compared to a group of children who were cCMV negative at birth. Data were collected about their health and development up to age 6 years. Parents of 73 693 children were invited to participate, and 32 486 (44·1%) gave informed consent for testing of their child's dried blood spot for CMV. Of the 31 484 dried blood spots tested, 156 (0·5%) were positive for cCMV. Of these, four (2·6%) children had been diagnosed with cCMV prior to this study. This unique retrospective nationwide study permits the estimation of long-term sequelae of cCMV up to the age of 6 years. The birth prevalence of cCMV in this study was 0·5%, which is in line with prior estimates. Most (97·4%) children with cCMV had not been diagnosed earlier, indicating under-diagnosis of cCMV.
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