Evidence map›Paper›PMID 26554670›Full record

Trial reportTrials2015

The effect of Transcranial Direct Current Stimulation in addition to Tinnitus Retraining Therapy for treatment of chronic tinnitus patients: a study protocol for a double-blind controlled randomised trial.

Sarah Rabau, Vincent Van Rompaey, Paul Van de Heyning

2 registry-linked trialsOpen access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Trials, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
1.0field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02285803 nacompletednot on this map

The Effect of Transcranial Direct Current Stimulation (tDCS) in Addition to Tinnitus Retraining Therapy (TRT) for Treatment of Chronic Tinnitus Patients

TypeinterventionalSponsorUniversity Hospital, AntwerpRan2014 to 2016ConditionsTinnitusArmstranscranial direct current stimulation (tDCS)
NCT04551404 nacompletednot on this mapstarted 2021, after this paper: background citation

Transcranial Electrical and Acoustic Stimulation for Tinnitus: A Randomized Double Blind Clinical Trial

TypeinterventionalSponsorUniversity of ZurichRan2021 to 2025Enrolled35ConditionsTinnitus, Tinnitus, SubjectiveArmstranscranial Random Noise Stimulation (tRNS) with acoustic stimulation (AS), transcranial Random Noise Stimulation (tRNS) without acoustic stimulation (AS)
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 16 citations in OpenAlex.

  1. Guideline
  2. Pooled it
  3. Trial
  4. Article
  5. Article
  6. [Improving the role of rTMS and tDCS in the treatment of chronic tinnitus by combining other rehabilitation techniques].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2021
    Review
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Sarah RabauFaculty of Medicine and Health Sciences, Campus Drie Eiken, University of Antwerp, Antwerp, Belgium. sarah.rabau@uantwerpen.be.
Vincent Van RompaeyFaculty of Medicine and Health Sciences, Campus Drie Eiken, University of Antwerp, Antwerp, Belgium. Vincent.vanrompaey@uza.be.
Paul Van de HeyningFaculty of Medicine and Health Sciences, Campus Drie Eiken, University of Antwerp, Antwerp, Belgium. paul.vandeheyning@uza.be.
University of Antwerp · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCurrently, there still is no treatment that eliminates tinnitus in all patients. Recent studies have shown that Tinnitus Retraining Therapy (TRT) significantly improves quality of life for tinnitus patients. Also, several studies have reported that transcranial Direct Current Stimulation (tDCS) has a positive effect on attention, working memory, long-term memory and other cognitive processes. The aim of this randomised placebo-controlled double-blind study is to evaluate the added effect of tDCS to TRT in chronic tinnitus patients. To our knowledge, this is the first study to combine both methods.

methodsPatients with chronic, non-pulsatile tinnitus will be randomised in two treatment groups: TRT and real tDCS versus TRT and sham tDCS. Evaluations will take place at baseline before therapy starts, at the end of the TRT and 3 months after therapy starts. The Tinnitus Functional Index will be used as the primary outcome measurement. Secondary outcome measurements will be the Visual Analogue Scale of Loudness, Hospital Anxiety and Depression Scale (HADS), Hyperacusis Questionnaire, psychoacoustic measurements and Event-related potential (ERP). DISCUSSION: To our knowledge this is the first study to combine TRT and tDCS. The objective is to evaluate whether tDCS can provide faster and/or more relief from the annoyance experienced in chronic tinnitus patients' daily lives. The advantage of the study is that it is double-blind and placebo-controlled.

trial registrationThe present study protocol was registered on 31 October 2014 at Clinicaltrials.gov: NCT02285803 .

Indexed as

Auditory PerceptionCounselingTranscranial Direct Current StimulationAcoustic StimulationActivities of Daily LivingAdaptation, PhysiologicalAttentionBelgiumChronic DiseaseClinical ProtocolsCognitionCombined Modality TherapyDouble-Blind MethodHumansMemoryPerceptual Masking

Identifiers

PMID26554670
PMCPMC4641380
OpenAlexW2144453490

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.