Observational studyArthritis care & research2016
Race- and Sex-Specific Incidence Rates and Predictors of Total Knee Arthroplasty: Seven-Year Data From the Osteoarthritis Initiative.
Observational study in Arthritis care & research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 47 citations in OpenAlex.
- Trial
- Investigating the Sexual Dimorphism of Waist-to-Hip Ratio and Its Associations with Complex Traits.Genes · 2025Article
- Evaluating the Disparate Use of Knee Arthroplasty Among Minorities Using Social Vulnerability Index.Arthroplasty today · 2025Article
- Disparities in Total Knee and Total Hip Arthroplasty Rates in the Population of Alaska, 2015 to 2018.Arthritis care & research · 2024Article
- Racial variations in complications and costs following total knee arthroplasty: a retrospective matched cohort study.Archives of orthopaedic and trauma surgery · 2024Article
- Early- to Mid-Term Review of a Prospective, Multi-Center, International, Outcomes Study of an Anatomically Designed Implant with Posterior-Stabilized Bearing in Total Knee Arthroplasty.Medicina (Kaunas, Lithuania) · 2023Article
- Factors Related to Expectations in Individuals Waiting for Total Knee Arthroplasty.Physiotherapy Canada. Physiotherapie Canada · 2023Article
- Investigating the Relationship Between Physical Activity Disparities and Health-Related Quality of Life Among Black People With Knee Osteoarthritis.Preventing chronic disease · 2023Article
- Advanced glycation end-product accumulation differs by location and sex in aged osteoarthritic human menisci.Osteoarthritis and cartilage · 2023Article
- Racial Disparities in Elective Total Joint Arthroplasty for Osteoarthritis.ACR open rheumatology · 2022Review
- Racial Disparities in Total Joint Arthroplasty.Current reviews in musculoskeletal medicine · 2021Review
- A Mediation Appraisal of Catastrophizing, Pain-Related Outcomes, and Race in Adults With Knee Osteoarthritis.The journal of pain · 2021Article
- Racial/Ethnic and Socioeconomic Disparities in Osteoarthritis Management.Rheumatic diseases clinics of North America · 2021Review
- Protocol for systematic review: patient decision aids for total hip and knee arthroplasty decision-making.Systematic reviews · 2021Article
- Everyday Discrimination in Adults with Knee Pain: The Role of Perceived Stress and Pain Catastrophizing.Journal of pain research · 2020Article
- Chondroprotective Factors in Osteoarthritis: a Joint Affair.Current rheumatology reports · 2019Review
- Racial and ethnic differences in the experience and treatment of noncancer pain.Pain management · 2019Review
- Disparities in Total Knee Replacement: Population Losses in Quality-Adjusted Life-Years Due to Differential Offer, Acceptance, and Complication Rates for African Americans.Arthritis care & research · 2018Article
- A Fresh Perspective on a Familiar Problem: Examining Disparities in Knee Osteoarthritis Using a Markov Model.Medical care · 2017Review
- Number of Persons With Symptomatic Knee Osteoarthritis in the US: Impact of Race and Ethnicity, Age, Sex, and Obesity.Arthritis care & research · 2016Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveTo determine race- and sex-specific rates of total knee arthroplasty (TKA) and to document independent effects of demographic factors on TKA incidence in a population with radiographically confirmed osteoarthritis (OA).
methodsWe used data from the Osteoarthritis Initiative, a US-based, multicenter longitudinal study of knee OA. We selected subjects with radiographic symptomatic OA at baseline and determined TKA incidence rates (ratio of TKAs to time at risk for TKA) over 84 months of followup. We used multivariable Poisson regression to identify independent associations between demographic factors and TKA utilization.
resultsDuring the study period there were 223 TKAs among 1,915 subjects for an incidence of 1.9% (95% confidence interval [95% CI] 1.7-2.2%). The overall rate was 1.9% (95% CI 1.5-2.3%) in men versus 2.0% (95% CI 1.7-2.3%) in women, and 2.2% (95% CI 1.9-2.6%) in whites versus 1.0% (95% CI 0.7-1.5%) in nonwhites. We observed a statistically significant interaction between sex and age (stratified at <65 and ≥65 years at end of followup), wherein male sex was associated with decreased risk of TKA for younger participants (relative risk [RR] 0.32) but not for older participants. Nonwhite race was associated with a decreased risk of TKA for both younger (RR 0.32) and older (RR 0.43) participants.
conclusionOur finding that nonwhites were less likely to undergo TKA than whites in adjusted analyses confirms racial differences observed in population-based studies and underscores the need for interventions to address lower use of TKA among nonwhites with OA.
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Registered trials
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