ArticleJournal of the American Medical Informatics Association : JAMIA2016
Identifying opportunities in EHR to improve the quality of antibiotic allergy data.
Article in Journal of the American Medical Informatics Association : JAMIA, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.
- The Use of Electronic Health Records to Study Drug-Induced Hypersensitivity Reactions from 2000 to 2021: A Systematic Review.Immunology and allergy clinics of North America · 2022Pooled it
- The combined use of natural language processing and electronic health records data to identify historical tolerances of β-lactams and promote clinician confidence in future use.Health systems (Basingstoke, England) · 2026Article
- Current status and challenges in the assessment of antibiotic allergy information in electronic health records: a retrospective observational study of perioperative patients.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2026Article
- Clinical Impact and Management of Antibiotic Allergy in Pregnancy.Current allergy and asthma reports · 2025Review
- A systematic review on how primary care electronic medical record data have been used for antimicrobial stewardship.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2025Review
- Article
- Dynamic reaction picklist for improving allergy reaction documentation: A usability study.International journal of medical informatics · 2023Article
- Beyond antibiotic prescribing rates: first-line antibiotic selection, prescription duration, and associated factors for respiratory encounters in urgent care.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2023Article
- Beta-lactam comprehensive allergy management program in a community medical center.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2023Article
- Factors Associated With Penicillin Allergy Labels in Electronic Health Records of Children in 2 Large US Pediatric Primary Care Networks.JAMA network open · 2022Article
- Article
- Differences in beta-lactam and penicillin allergy: Beyond the West and focusing on Asia-Pacific.Frontiers in allergy · 2022Review
- β-lactam exposure outcome among patients with a documented allergy to penicillins post-implementation of a new electronic medical record system and alerting rules.Journal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada · 2021Article
- Antibiotic allergy labels in hospitalized and critically ill adults: A review of current impacts of inaccurate labelling.British journal of clinical pharmacology · 2019Review
- Exploring the nurses' role in antibiotic stewardship: A multisite qualitative study of nurses and infection preventionists.American journal of infection control · 2018Article
- Associations between bacterial infections and blood pressure in pregnancy.Pregnancy hypertension · 2017Article
- Poor reporting and documentation in drug-associated Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis - Lessons for medication safety.British journal of clinical pharmacology · 2017Observational
- Improving Antimicrobial Stewardship by Antibiotic Allergy Delabeling: Evaluation of Knowledge, Attitude, and Practices Throughout the Emerging Infections Network.Open forum infectious diseases · 2016Article
- An Investigation of Radiation Treatment Learning Opportunities in Relation to the Radiation Oncology Electronic Medical Record: A Single Institution Experience.Advances in radiation oncologyArticle
- The 3 Cs of Antibiotic Allergy-Classification, Cross-Reactivity, and Collaboration.The journal of allergy and clinical immunology. In practiceReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAntimicrobial resistance is a growing, global public health crisis, due in large part to the overuse and misuse of antibiotics. Understanding medication allergy data and allergy reactions that are documented in electronic health records (EHRs) can help to identify opportunities to improve the quality of documentation of beta-lactam allergies, thus potentially reducing the prescribing of alternative antibiotics.
methodsMedication allergies and allergy reactions recorded in the EHR for 319 051 patients seen across 32 community health centers were reviewed. Patients with a beta-lactam allergy recorded in their EHR were identified. Free text, as well as standardized allergy and allergy reaction fields, were analyzed.
resultsAmong patients, 9.1% (n = 29 095) had evidence of a beta-lactam allergy recorded in their EHR. Women, white, and non-Hispanic patients were more likely to have a documented allergy compared to men, black, and Hispanic patients. Among all patients with a documented beta-lactam allergy, 36.2% had an empty or missing allergy reaction description in their EHR.
conclusionsFindings suggest that current EHR documentation practices among the health centers reviewed do not provide enough information on allergic reactions to allow providers to discern between true allergies and common, but anticipated, drug side effects. Improved EHR documentation guidance, training that reinforces the use of standardized data and more detailed recording of allergic reactions, combined with initiatives to address patient barriers including health literacy, may help to improve the accuracy of drug allergies in patients' records. These initiatives, combined with antimicrobial stewardship programs, can help to reduce inappropriate prescribing of alternative antibiotics when beta-lactam antibiotics are first-line and can be tolerated.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.