ReviewDeutsches Arzteblatt international2015
The Diagnosis and Treatment of Ectopic Pregnancy.
Review in Deutsches Arzteblatt international, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
52 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The clinical efficacy and impact on fertility function of laparoscopic surgery versus methotrexate for treatment of tubal pregnancy: a meta-analysis.Biomedical engineering online · 2025Pooled it
- Early (Days 1-4) post-treatment serum hCG level changes predict single-dose methotrexate treatment success in tubal ectopic pregnancy.Human reproduction (Oxford, England) · 2023Trial
- Multiple Regression Analysis of Ultrasound and Clinical Features for Quantitative Evaluation of Tubal Pregnancy Rupture.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2026Review
- ESR Essentials: Gynaecological causes of acute pelvic pain in women: a primer for emergent evaluation-practice recommendations by the European Society of Emergency Radiology.European radiology · 2025Review
- A Case of Ectopic Pregnancy With an Unusually High Level of β-hCG Correlating With Normal Pregnancy.Cureus · 2025Article
- Multimodality imaging techniques of diaphragmatic ectopic pregnancy: a case report and review of the literature.Journal of medical case reports · 2025Review
- Kisspeptin and neurokinin B: roles in reproductive health.Physiological reviews · 2025Review
- Laryngospasm During Anesthesia in Emergency Surgery for Ruptured Ectopic Pregnancy: A Case Report.Clinical case reports · 2025Article
- Childbearing and Pregnancy Trends Among Female Plastic and Orthopedic/Trauma Surgeons in German-speaking Countries.Plastic and reconstructive surgery. Global open · 2025Article
- Effect of Single and Multiple Methotrexate Doses Treatment on Ovarian Reserve in Ectopic Pregnancy Women: A Prospective Cohort Study.Journal of obstetrics and gynaecology of India · 2025Article
- [Guideline project termination of pregnancy in the first trimester].Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz · 2025Article
- Ectopic pregnancy.Nature reviews. Disease primers · 2024Review
- Glutathione-Responsive Methotrexate Polymersomes for Potential Management of Ectopic Pregnancy.Small (Weinheim an der Bergstrasse, Germany) · 2024Article
- Non-tubal ectopic pregnancy treatment experiences of a tertiary care center.Archives of gynecology and obstetrics · 2024Article
- Rectal ectopic pregnancy: A case report.International journal of surgery case reports · 2024Article
- Management of Interstitial Ectopic Pregnancy in a Bicornuate Uterus Simulating an Incomplete Abortion.Cureus · 2024Article
- Medical management of ectopic pregnancy: Case series at a private tertiary hospital, Tanzania.SAGE open medical case reports · 2024Article
- Ectopic Pregnancy in the Round Ligament Following Bilateral Salpingectomy: A Case Report.Cureus · 2023Article
- Evidence for a case-based module in the low-resource setting to teach ectopic pregnancy management.Surgery in practice and science · 2023Article
- A Rare Case of Methotrexate Induced Pancreatitis in Ectopic Pregnancy.Ewha medical journal · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundExtrauterine pregnancy is a complication of the first trimester of pregnancy that arises in 1.3-2.4% of all pregnancies.
methodsThis review is based on articles and guidelines retrieved by a selective PubMed search.
resultsThe presentation of extrauterine pregnancy is highly variable, ranging from an asymptomatic state, to pelvic pain that is worse on one side, to tubal rupture with hemorrhagic shock. 75% of tubal pre gnancies can be detected by transvaginal ultrasonography. In patients with a vital extrauterine pregnancy, the human chorionic gonadotropin concentration generally doubles within 48 hours. Laparoscopy is the gold standard of treatment. Two randomized, controlled trials comparing organ-preserving treatment with ablative surgery revealed no significant difference in pregnancy rates after the intervention, but precise details of the surgical procedures were not provided, and long-term fertility data are lacking. Metho - trexate therapy should be used only for strict indications.
conclusionFurther randomized, controlled trials with longer follow-up will be needed to answer currently open questions about the potential for individualized surgical treatment and the proper role of pharmacotherapy.
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