ArticleProceedings of the National Academy of Sciences of the United States of America2015
Central role for ferritin in the day/night regulation of iron homeostasis in marine phytoplankton.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed, 54 citations in OpenAlex.
- Biological and genomic resources for the cosmopolitan phytoplankton Bathycoccus: insights into genetic diversity and function of outlier chromosomes.The Plant journal : for cell and molecular biology · 2026Article
- Chloroplast-mitochondria synergy modulates responses to iron limitation in twoISME communications · 2026Article
- Identification, characterization, and function analysis of the VIT family in Phaeodactylum tricornutum.Scientific reports · 2025Article
- Latitudinal diversity in circadian and light-sensing genes in an ecologically vital group of marine picoeukaryote algae.The ISME journal · 2025Article
- A Brief History of Ferritin, an Ancient and Versatile Protein.International journal of molecular sciences · 2024Review
- Microeukaryote metabolism across the western North Atlantic Ocean revealed through autonomous underwater profiling.Nature communications · 2024Article
- Hidden genomic diversity drives niche partitioning in a cosmopolitan eukaryotic picophytoplankton.The ISME journal · 2024Article
- Short-term acidification promotes diverse iron acquisition and conservation mechanisms in upwelling-associated phytoplankton.Nature communications · 2023Article
- Bioavailable iron titrations reveal oceanic Synechococcus ecotypes optimized for different iron availabilities.ISME communications · 2022Article
- Article
- Comparative proteomics analysis ofFrontiers in cellular and infection microbiology · 2022Article
- Iron metabolism strategies in diatoms.Journal of experimental botany · 2021Review
- Life in fluctuating environments.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2020Review
- Dynamic genome evolution and complex virocell metabolism of globally-distributed giant viruses.Nature communications · 2020Article
- Iron Uptake Mechanisms in Marine Phytoplankton.Frontiers in microbiology · 2020Review
- Microbial iron metabolism as revealed by gene expression profiles in contrasted Southern Ocean regimes.Environmental microbiology · 2019Article
- Simplified Transformation ofGenes · 2019Article
- Different iron storage strategies among bloom-forming diatoms.Proceedings of the National Academy of Sciences of the United States of America · 2018Article
- Iron Sulfur and Molybdenum Cofactor Enzymes Regulate theFrontiers in physiology · 2018Article
- Regulating cellular trace metal economy in algae.Current opinion in plant biology · 2017Review
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Authors and funding
15 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In large regions of the open ocean, iron is a limiting resource for phytoplankton. The reduction of iron quota and the recycling of internal iron pools are among the diverse strategies that phytoplankton have evolved to allow them to grow under chronically low ambient iron levels. Phytoplankton species also have evolved strategies to cope with sporadic iron supply such as long-term storage of iron in ferritin. In the picophytoplanktonic species Ostreococcus we report evidence from observations both in the field and in laboratory cultures that ferritin and the main iron-binding proteins involved in photosynthesis and nitrate assimilation pathways show opposite diurnal expression patterns, with ferritin being maximally expressed during the night. Biochemical and physiological experiments using a ferritin knock-out line subsequently revealed that this protein plays a central role in the diel regulation of iron uptake and recycling and that this regulation of iron homeostasis is essential for cell survival under iron limitation.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.