Evidence map›Paper›PMID 26553564›Full record

ReviewVeterinary immunology and immunopathology2015

Natural killer cells in host defense against veterinary pathogens.

Sudhanshu Shekhar, Xi Yang

Abstract readReview
In one paragraph

Review in Veterinary immunology and immunopathology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Review
  3. Mucosal Immune System of Cattle: All Immune Responses Begin Here.The Veterinary clinics of North America. Food animal practice · 2019
    Review
  4. Review
  5. Enteric Immunity: Happy Gut, Healthy Animal.The Veterinary clinics of North America. Food animal practice · 2018
    Review
  6. Article
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Sudhanshu ShekharDepartments of Medical Microbiology and Immunology, Faculty of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada. Electronic address: umshekha@myumanitoba.ca.
Xi YangDepartments of Medical Microbiology and Immunology, Faculty of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada.
University of Manitoba · CA

Funding

Canadian Institutes of Health Research
6 · The paper itself

Abstract

Natural Killer (NK) cells constitute a major subset of innate lymphoid cells that do not express the T- and B-cell receptors and play an important role in antimicrobial defense. NK cells not only induce early and rapid innate immune responses, but also communicate with dendritic cells to shape the adaptive immunity, thus bridging innate and adaptive immunity. Although the functional biology of NK cells is well-documented in a variety of infections in humans and mice, their role in protecting domestic animals from infectious agents is only beginning to be understood. In this article, we summarize the current state of knowledge about the contribution of NK cells in pathogen defense in domestic animals, especially cattle and pigs. Understanding the immunobiology of NK cells will translate into strategies to manipulate these cells for preventive and therapeutic purposes.

Indexed as

Animal DiseasesAnimalsAnimals, DomesticCattleFoot-and-Mouth DiseaseHost-Pathogen InteractionsImmunity, InnateKiller Cells, NaturalModels, ImmunologicalMycobacterium bovisProtozoan Infections, AnimalSus scrofaTuberculosisTuberculosis, BovineVirus DiseasesDomestic animalsImmunityInnate lymphoid cellsNK cellsPathogens

Identifiers

PMID26553564
PMCPMC7112915
OpenAlexW2184308515

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.