Evidence map›Paper›PMID 26553309›Full record

ArticleScientific reports2015

Construction of a high-density linkage map and fine mapping of QTL for growth in Asian seabass.

Le Wang, Zi Yi Wan, Bin Bai, Shu Qing Huang, Elaine Chua, May Lee, Hong Yan Pang, Yan Fei Wen, Peng Liu, Feng Liu and 4 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed
11.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 116 citations in OpenAlex.

  1. Article
  2. Article
  3. Mutations Upstream of ppp2ca Affect Body Weight in Asian Seabass.Marine biotechnology (New York, N.Y.) · 2025
    Article
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  9. Combination of GWAS and FMolecular genetics and genomics : MGG · 2023
    Article
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  13. Scale Drop Disease Virus (SDDV) andFrontiers in genetics · 2021
    Article
  14. Review
  15. Article
  16. Article
  17. Article
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  19. Article
  20. Article

3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Le WangTemasek Life Sciences Laboratory, National University of Singapore, 1 Research Link, Singapore 117604.
Zi Yi WanTemasek Life Sciences Laboratory, National University of Singapore, 1 Research Link, Singapore 117604.
Bin BaiTemasek Life Sciences Laboratory, National University of Singapore, 1 Research Link, Singapore 117604.
Shu Qing HuangTemasek Life Sciences Laboratory, National University of Singapore, 1 Research Link, Singapore 117604.
Elaine ChuaTemasek Life Sciences Laboratory, National University of Singapore, 1 Research Link, Singapore 117604.
May LeeTemasek Life Sciences Laboratory, National University of Singapore, 1 Research Link, Singapore 117604.
Hong Yan PangTemasek Life Sciences Laboratory, National University of Singapore, 1 Research Link, Singapore 117604.
Yan Fei WenTemasek Life Sciences Laboratory, National University of Singapore, 1 Research Link, Singapore 117604.
Peng LiuTemasek Life Sciences Laboratory, National University of Singapore, 1 Research Link, Singapore 117604.
Feng LiuTemasek Life Sciences Laboratory, National University of Singapore, 1 Research Link, Singapore 117604.
Fei SunTemasek Life Sciences Laboratory, National University of Singapore, 1 Research Link, Singapore 117604.
Grace LinTemasek Life Sciences Laboratory, National University of Singapore, 1 Research Link, Singapore 117604.
Bao Qing YeTemasek Life Sciences Laboratory, National University of Singapore, 1 Research Link, Singapore 117604.
Gen Hua YueTemasek Life Sciences Laboratory, National University of Singapore, 1 Research Link, Singapore 117604.
National University of Singapore · SGTemasek Life Sciences Laboratory · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A high-density genetic map is essential for comparative genomic studies and fine mapping of QTL, and can also facilitate genome sequence assembly. Here, a high density genetic map of Asian seabass was constructed with 3321 SNPs generated by sequencing 144 individuals in a F2 family. The length of the map was 1577.67 cM with an average marker interval of 0.52 cM. A high level of genomic synteny among Asian seabass, European seabass, Nile tilapia and stickleback was detected. Using this map, one genome-wide significant and five suggestive QTL for growth traits were detected in six linkage groups (i.e. LG4, LG5, LG11, LG13, LG14 and LG15). These QTL explained 10.5-16.0% of phenotypic variance. A candidate gene, ACOX1 within the significant QTL on LG5 was identified. The gene was differentially expressed between fast- and slow-growing Asian seabass. The high-density SNP-based map provides an important tool for fine mapping QTL in molecular breeding and comparative genome analysis.

Indexed as

Chromosome MappingGenetic LinkageQuantitative Trait, HeritableQuantitative Trait LociAnimalsBassComputational BiologyFemaleGenomicsHigh-Throughput Nucleotide SequencingLod ScoreMaleMolecular Sequence AnnotationPolymorphism, Single NucleotideRecombination, Genetic

Identifiers

PMID26553309
PMCPMC4639833
OpenAlexW2168113943

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.