Evidence map›Paper›PMID 26553290›Full record

ArticleAlcohol and alcoholism (Oxford, Oxfordshire)2016

Adverse Childhood Experiences and Alcohol Consumption in Midlife and Early Old-Age.

Jessica Pui Kei Leung, Annie Britton, Steven Bell

Open access · bronzeAbstract read
In one paragraph

Article in Alcohol and alcoholism (Oxford, Oxfordshire), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.1field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 29 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jessica Pui Kei LeungResearch Department of Epidemiology and Public Health, University College London, London, UK rmjlleu@ucl.ac.uk.
Annie BrittonResearch Department of Epidemiology and Public Health, University College London, London, UK.
Steven BellResearch Department of Epidemiology and Public Health, University College London, London, UK.
University College London · GB

Funding

CHANGES IN HEALTH: SOCIO-ECONOMIC STATUS AND PATHWAYSR37AG013196 · NIA · UNIVERSITY OF LONDON INST OF NEUROLOGY · PI MARMOT, MICHAEL G · 1999 to 2008
$4.3M
Socio-economic status and heterogeneity in agingR01AG013196 · NIA · UNIVERSITY OF LONDON INST OF NEUROLOGY · PI MARMOT, MICHAEL G, SINGH-MANOUX, ARCHANA · 1996 to 2013
$3.5M
Socioeconomic gradient in CHD in early old ageR01HL036310 · NHLBI · UNIVERSITY OF LONDON · PI KIVIMAKI, MIKA J, MARMOT, MICHAEL G · 1986 to 2012
$3.1M
Health behaviors over the adult lifecourse and cognitive agingR01AG034454 · NIA · UNIVERSITY COLLEGE LONDON · PI KIVIMAKI, MIKA J, SINGH-MANOUX, ARCHANA · 2009 to 2013
$1.5M
British Heart Foundation RG/07/008/23674British Heart Foundation RG/13/2/30098Medical Research Council MR/K013351/1Medical Research Council MR/M006638/1NHLBI NIH HHS HL036310NIA NIH HHS AG034454NIA NIH HHS AG13196PHS HHS K013351
6 · The paper itself

Abstract

aimsTo examine the individual and cumulative effects of adverse childhood experiences (ACEs) on alcohol consumption in midlife and early old-age, and the role of ACEs in 10-year drinking trajectories across midlife.

methodsData were from the Whitehall II study, a longitudinal British civil service-based cohort study (N = 7870, 69.5% male). Multinomial logistic regression was used to examine the individual and cumulative effects of ACEs on weekly alcohol consumption. Mixed-effect multilevel modelling was used to explore the relationship between ACEs and change in alcohol consumption longitudinally.

resultsParticipants who were exposed to parental arguments/fights in childhood were 1.24 (95% CI 1.06, 1.45) times more likely to drink at hazardous levels in midlife (mean age 56 years) after controlling for covariates and other ACEs. For each additional exposure to an ACE, the risk of hazardous drinking versus moderate drinking was increased by 1.12 (95% CI 1.03, 1.21) after adjusting for sex, age, adult socio-economic status, ethnicity and marital status. No associations between ACEs and increased risk of hazardous drinking in early old-age (mean age 66 years) were found. In longitudinal analyses, ACEs did not significantly influence 10-year drinking trajectories across midlife.

conclusionThe effect of exposure to parental arguments on hazardous drinking persists into midlife.

Indexed as

Adult Survivors of Child AbuseAgedAged, 80 and overAgingAlcohol DrinkingFemaleHumansLongitudinal StudiesMaleMiddle AgedModels, Psychological

Identifiers

PMID26553290
PMCPMC4830410
OpenAlexW2174681457

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.