Evidence map›Paper›PMID 26552776›Full record

ReviewBest practice & research. Clinical gastroenterology2015

An allergist's perspective to the evaluation of Eosinophilic Esophagitis.

Jonathan M Spergel

Open access · greenAbstract readReview
In one paragraph

Review in Best practice & research. Clinical gastroenterology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Eosinophilic esophagitis.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2024
    Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Review
  10. Review
  11. Eosinophilic esophagitis during sublingual and oral allergen immunotherapy.Current opinion in allergy and clinical immunology · 2019
    Review
  12. Eosinophilic esophagitis incidence in New Zealand: high but not increasing.Clinical and experimental gastroenterology · 2019
    Article
  13. Correction to: Eosinophilic esophagitis.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2019
    Article
  14. Review
  15. Review
  16. Article
  17. Review
  18. Eosinophilic esophagitis.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2018
    Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Jonathan M SpergelPerelman School of Medicine, University of Pennsylvania, Division of Allergy, Immunology, and Infectious Diseases, The Children's Hospital of Philadelphia, Philadelphia, PA, USA. Electronic address: spergel@email.chop.edu.
Children's Hospital of Philadelphia · US

Funding

TRAINING (CAREER DEVELOPMENT) COMPONENTU54AI117804 · NIAID · CINCINNATI CHILDRENS HOSP MED CTR · PI JONATHAN Micheal SPERGEL · 2014 to 2026
$18.5M
NIAID NIH HHS U54 AI117804
6 · The paper itself

Abstract

Eosinophilic Esophagitis (EoE) is a classic atopic disease as it shares features with other atopic disease on all levels including pathogenesis, genetics, epidemiology, and treatment options. EoE has elements of Th2 pathogenesis with increase levels of Th2 cytokines (IL4, 5, and 13). In addition, it shares atopic genetic risk factors including thymic stromal lymphopoietin (TSLP) loci as a risk factor in genome wide association studies. EoE patients have a higher rate of other atopic disease (asthma, allergic rhinitis and food allergy) compared to the general population indicating their atopic phenotype. Like asthma, atopic dermatitis or food allergy, EoE has increased in the last 20 years. Treatment options include the basic principle of other atopic diseases include using topical steroids or avoidance of the triggers (food or pollen). An allergist provides a critical role as they are experts in the treatment of atopic disease including avoidance strategies.

Indexed as

Air PollutantsAllergensAllergy and ImmunologyEosinophilic EsophagitisFood HypersensitivityHumansIntradermal TestsPatch TestsPollenRisk FactorsAir PollutantsAllergensAeroallergensAtopy patch testingEosinophilic EsophagitisFood allergySkin prick testing

Identifiers

PMID26552776
PMCPMC4641822
OpenAlexW2150533866

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.