ArticleScientific reports2015
Peptide Functionalized Gold Nanorods for the Sensitive Detection of a Cardiac Biomarker Using Plasmonic Paper Devices.
Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed.
- Ultrasound-enabled refreshable electrochemical sensors for cardiac biomarker monitoring.Biosensors & bioelectronics · 2026Article
- Dual colorimetric-photothermal lateral flow immunoassay based on Au@Pt nanozymes for sensitive detection of cardiac troponin I.Mikrochimica acta · 2026Article
- Two-Dimensional MoSACS applied materials & interfaces · 2025Article
- Paper-Based Sensors: Fantasy or Reality?Nanomaterials (Basel, Switzerland) · 2025Review
- Antigen-Mimic Nanoparticles in Ultrasensitive on-Chip Integrated Anti-p53 Antibody Quantification.ACS sensors · 2024Article
- Polyethylene Glycol-Mediated Directional Conjugation of Biological Molecules for Enhanced Immunoassays at the Point-of-Care.Polymers · 2023Article
- Cardiovascular biomarkers in body fluids: progress and prospects in optical sensors.Biophysical reviews · 2022Review
- Significance of Cardiac Troponins as an Identification Tool in COVID-19 Patients Using Biosensors: An Update.Frontiers in molecular biosciences · 2022Review
- A review of cardiac troponin I detection by surface enhanced Raman spectroscopy: Under the spotlight of point-of-care testing.Frontiers in chemistry · 2022Review
- Paper-based plasmonic substrates as surface-enhanced Raman scattering spectroscopy platforms for cell culture applications.Materials today. Bio · 2021Review
- Stabilization of surface-bound antibodies for ELISA based on a reversable zeolitic imidazolate framework-8 coating.Journal of colloid and interface science · 2021Article
- Periodic arrays of plasmonic crossed-bowtie nanostructures interspaced with plasmonic nanocrosses for highly sensitive LSPR based chemical and biological sensing.RSC advances · 2021Article
- Gold Nanorods for LSPR Biosensing: Synthesis, Coating by Silica, and Bioanalytical Applications.Biosensors · 2020Review
- Development of a specific troponin I detection system with enhanced immune sensitivity using a single monoclonal antibody.Royal Society open science · 2020Article
- PRADA: Portable Reusable Accurate Diagnostics with nanostar Antennas for multiplexed biomarker screening.Bioengineering & translational medicine · 2020Article
- Hybrid Plasmonic Fiber-Optic Sensors.Sensors (Basel, Switzerland) · 2020Review
- Refreshable Nanobiosensor Based on Organosilica Encapsulation of Biorecognition Elements.ACS applied materials & interfaces · 2020Article
- Bioplasmonic paper-based assay for perilipin-2 non-invasively detects renal cancer.Kidney international · 2019Article
- Nanoscale Technologies for Prevention and Treatment of Heart Failure: Challenges and Opportunities.Chemical reviews · 2019Review
- Point of care testing for infectious diseases.Clinica chimica acta; international journal of clinical chemistry · 2019Review
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The sensitivity of localized surface plasmon resonance (LSPR) of metal nanostructures to adsorbates lends itself to a powerful class of label-free biosensors. Optical properties of plasmonic nanostructures are dependent on the geometrical features and the local dielectric environment. The exponential decay of the sensitivity from the surface of the plasmonic nanotransducer calls for the careful consideration in its design with particular attention to the size of the recognition and analyte layers. In this study, we demonstrate that short peptides as biorecognition elements (BRE) compared to larger antibodies as target capture agents offer several advantages. Using a bioplasmonic paper device (BPD), we demonstrate the selective and sensitive detection of the cardiac biomarker troponin I (cTnI). The smaller sized peptide provides higher sensitivity and a lower detection limit using a BPD. Furthermore, the excellent shelf-life and thermal stability of peptide-based LSPR sensors, which precludes the need for special storage conditions, makes it ideal for use in resource-limited settings.
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