Evidence map›Paper›PMID 26552461›Full record

ArticleThe Korean journal of internal medicine2015

Predicting postoperative total calcium requirements after parathyroidectomy in secondary hyperparathyroidism.

Byung Heon Kang, Soon Young Hwang, Jeong Yeop Kim, Yu Ah Hong, Mi Yeon Jung, Eun Ah Lee, Ji Eun Lee, Jae Bok Lee, Gang Jee Ko, Heui Jung Pyo and 1 more

Open access · goldAbstract read
In one paragraph

Article in The Korean journal of internal medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Byung Heon KangDivision of Nephrology, Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea.
Soon Young HwangDepartment of Biostatistics, Korea University College of Medicine, Seoul, Korea.
Jeong Yeop KimDivision of Nephrology, Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea.
Yu Ah HongDivision of Nephrology, Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea.
Mi Yeon JungDivision of Nephrology, Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea.
Eun Ah LeeDivision of Nephrology, Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea.
Ji Eun LeeDivision of Nephrology, Department of Internal Medicine, Hallym University College of Medicine, Chuncheon, Korea.
Jae Bok LeeDivision of Breast and Endocrine Surgery, Department of Surgery, Korea University College of Medicine, Seoul, Korea.
Gang Jee KoDivision of Nephrology, Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea.
Heui Jung PyoDivision of Nephrology, Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea.
Young Joo KwonDivision of Nephrology, Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea.
Korea University · KRHallym University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimsTo prevent hypocalcemia after parathyroidectomy (PTX), parenteral calcium is required in addition to oral calcitriol and calcium. After switching to oral calcium, patients can be discharged from the hospital. The aim of this study was to analyze the clinical characteristics and outcomes of PTX performed at a single Korean center and to investigate the associated laboratory factors used to analyze the total amount of postoperative calcium required.

methodsWe enrolled 91 hemodialysis patients undergoing PTX from November 2003 to December 2011. We collected clinical and laboratory data preoperatively, 12 and 48 hours postoperatively, at discharge, and 3 and 6 months postoperatively.

resultsIn total, 59 patients underwent PTX with autotransplantation (AT), 6 underwent total PTX without AT, 11 underwent subtotal PTX, and 15 underwent limited PTX. Total PTX without AT showed the lowest recurrence rate. At all postoperative time points, the mean levels of serum calcium, phosphorus, and intact parathyroid hormone (iPTH) decreased significantly, compared with preoperative levels; however, alkaline phosphatase (ALP) increased significantly from 48 hours postoperatively to discharge (p < 0.001). On multiple linear regression analysis, the total amount of injected calcium during hospitalization showed a significant correlation with preoperative ALP (p < 0.001), preoperative iPTH (p = 0.037), and Δphosphorus at 48 hours (p < 0.001). We developed an equation for estimating the total calcium requirement after PTX.

conclusionsPreoperative ALP, preoperative iPTH, and Δphosphorus at 48 hours may be significant factors in estimating the postoperative calcium requirement. The formula for postoperative calcium requirement after PTX may help to predict the duration of postoperative hospitalization.

Indexed as

Decision Support TechniquesDietary SupplementsAdministration, IntravenousAdministration, OralAdultAgedBiomarkersCalciumCalcium CarbonateCalcium CompoundsCalcium GluconateFemaleHumansHyperparathyroidism, SecondaryHypocalcemiaLactatesBiomarkersCalciumCalcium CarbonateCalcium CompoundsCalcium Gluconatecalcium lactateLactatesParathyroid HormonePhosphorusPTH protein, humanHyperparathyroidismKidney failure, chronicParathyroidectomySecondary

Identifiers

PMID26552461
PMCPMC4642015
OpenAlexW2121171888

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.