ArticleIEEE transactions on medical imaging2016
Determining the Performance of Fluorescence Molecular Imaging Devices Using Traceable Working Standards With SI Units of Radiance.
Article in IEEE transactions on medical imaging, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed.
- Real-time fidelity assessment of fluorescence molecular imaging without reference images.Journal of biomedical optics · 2026Article
- Reflect: reporting guidelines for preclinical, translational and clinical fluorescence molecular imaging studies.Npj imaging · 2025Article
- A multiresolution approach with method-informed statistical analysis for quantifying lymphatic pumping dynamics.Npj imaging · 2025Article
- Impact of signal-to-noise ratio and contrast definition on the sensitivity assessment and benchmarking of fluorescence molecular imaging systems.Journal of biomedical optics · 2025Article
- A novel flexible near-infrared endoscopic device that enables real-time artificial intelligence fluorescence tissue characterization.PloS one · 2025Article
- Tutorial on methods for estimation of optical absorption and scattering properties of tissue.Journal of biomedical optics · 2024Article
- A Review of Image Sensors Used in Near-Infrared and Shortwave Infrared Fluorescence Imaging.Sensors (Basel, Switzerland) · 2024Review
- Near-Infrared Fluorescence Tomography and Imaging of Ventricular Cerebrospinal Fluid Flow and Extracranial Outflow in Non-Human Primates.IEEE transactions on medical imaging · 2023Article
- Assessment of open-field fluorescence guided surgery systems: implementing a standardized method for characterization and comparison.Journal of biomedical optics · 2023Article
- Imaging peripheral lymphatic dysfunction in chronic conditions.Frontiers in physiology · 2023Review
- Autofluorescence detection and co-axial projection for intraoperative localization of parathyroid gland.Biomedical engineering online · 2022Article
- Criteria for the design of tissue-mimicking phantoms for the standardization of biophotonic instrumentation.Nature biomedical engineering · 2022Review
- Conversion of imager-specific response to tissue phantom fluorescence into system of units-traceable units.Journal of biomedical optics · 2022Article
- Standardization and implementation of fluorescence molecular endoscopy in the clinic.Journal of biomedical optics · 2022Article
- Review of consensus test methods in medical imaging and current practices in photoacoustic image quality assessment.Journal of biomedical optics · 2021Review
- 3D printing fluorescent material with tunable optical properties.Scientific reports · 2021Article
- The Development and Treatment of Lymphatic Dysfunction in Cancer Patients and Survivors.Cancers · 2020Review
- Performance test methods for near-infrared fluorescence imaging.Medical physics · 2020Article
- Indocyanine green matching phantom for fluorescence-guided surgery imaging system characterization and performance assessment.Journal of biomedical optics · 2020Article
- Assessing lymphatic route of CSF outflow and peripheral lymphatic contractile activity during head-down tilt using near-infrared fluorescence imaging.Physiological reports · 2020Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
To date, no emerging preclinical or clinical near-infrared fluorescence (NIRF) imaging devices for noninvasive and/or surgical guidance have their performances validated on working standards with SI units of radiance that enable comparison or quantitative quality assurance. In this work, we developed and deployed a methodology to calibrate a stable, solid phantom for emission radiance with International System of Units (SI) units of mW ·sr(-1) ·cm(-2) for use in characterizing the measurement sensitivity of ICCD and IsCMOS detection, signal-to-noise ratio, and contrast. In addition, at calibrated radiances, we assess transverse and lateral resolution of ICCD and IsCMOS camera systems. The methodology allowed demonstration of superior SNR of the ICCD over the IsCMOS technology and superior resolution of the IsCMOS over the ICCD approach. Contrast depended upon the camera settings (binning and integration time) and gain of intensifier. Finally, because the architecture of CMOS and CCD camera systems results in vastly different performance, we comment on the utility of these technologies for small animal imaging as well as clinical applications for noninvasive and surgical guidance.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.