Evidence map›Paper›PMID 26551969›Full record

ArticleAdvanced materials (Deerfield Beach, Fla.)2016

Highly Elastic and Conductive Human-Based Protein Hybrid Hydrogels.

Nasim Annabi, Su Ryon Shin, Ali Tamayol, Mario Miscuglio, Mohsen Afshar Bakooshli, Alexander Assmann, Pooria Mostafalu, Jeong-Yun Sun, Suzanne Mithieux, Louis Cheung and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced materials (Deerfield Beach, Fla.), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers.

0numbers the graph read from it
0cells of the map it votes in
72citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

72 citing papers in PubMed.

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12 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Nasim AnnabiBiomaterials Innovation Research Center, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Cambridge, MA, 02139, USA.
Su Ryon ShinBiomaterials Innovation Research Center, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Cambridge, MA, 02139, USA.
Ali TamayolBiomaterials Innovation Research Center, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Cambridge, MA, 02139, USA.
Mario MiscuglioBiomaterials Innovation Research Center, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Cambridge, MA, 02139, USA.
Mohsen Afshar BakooshliBiomaterials Innovation Research Center, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Cambridge, MA, 02139, USA.
Alexander AssmannBiomaterials Innovation Research Center, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Cambridge, MA, 02139, USA.
Pooria MostafaluBiomaterials Innovation Research Center, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Cambridge, MA, 02139, USA.
Jeong-Yun SunDepartment of Material Science and Engineering, Seoul National University, Seoul, 151-742, South Korea.
Suzanne MithieuxMolecular Bioscience, Charles Perkins Centre, Bosch Institute, University of Sydney, Sydney, NSW, 2006, Australia.
Louis CheungDepartment of Chemistry, University of Waterloo, Waterloo, Ontario, N2L 3G1, Canada.
Xiaowu Shirley TangDepartment of Chemistry, University of Waterloo, Waterloo, Ontario, N2L 3G1, Canada.
Anthony S WeissMolecular Bioscience, Charles Perkins Centre, Bosch Institute, University of Sydney, Sydney, NSW, 2006, Australia.
Ali KhademhosseiniBiomaterials Innovation Research Center, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Cambridge, MA, 02139, USA.

Funding

Microengineered Osteons for Bone Tissue EngineeringR01AR057837 · NIAMS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI YANG, YUNZHI · 2010 to 2018
$5.1M
3D combinatorial microenvironments for effective cell based therapyR01HL099073 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI KHADEMHOSSEINI, ALI, LIAO, RONGLIH · 2010 to 2013
$2.6M
Engineering Vascularized Bone Tissues By Microfabrication And ScaffoldingR01DE021468 · NIDCR · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI YANG, YUNZHI · 2011 to 2014
$1.8M
A Microfabrication Platform for Direct Printing Vascularized Functional Tissue CoR01EB012597 · NIBIB · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI CHEN, SHAOCHEN · 2010 to 2013
$1.4M
Multifunctional Tropoelastin-Silk Biomaterial SystemsR01EB014283 · NIBIB · TUFTS UNIVERSITY MEDFORD · PI KAPLAN, DAVID L. · 2012 to 2015
$1.2M
Microengineered Osteoinductive and Vasculogenic ScaffoldR56AR063745 · NIAMS · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI JABBARI, ESMAIEL · 2013 to 2014
$669k
A miniaturized model of human skin and lymph node for drug discovery and testingR56AI105024 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI KHADEMHOSSEINI, ALI · 2014 to 2014
$442k
NHLBI NIH HHS HL099073NHLBI NIH HHS R01 HL099073NIAID NIH HHS AI105024NIAID NIH HHS R56 AI105024NIAMS NIH HHS AR057837NIAMS NIH HHS AR063745NIAMS NIH HHS R01 AR057837NIAMS NIH HHS R56 AR063745NIBIB NIH HHS EB012597NIBIB NIH HHS EB014283NIBIB NIH HHS R01 EB012597NIBIB NIH HHS R01 EB014283NIDCR NIH HHS DE021468NIDCR NIH HHS R01 DE021468
6 · The paper itself

Abstract

A highly elastic hybrid hydrogel of methacryloyl-substituted recombinant human tropoelastin (MeTro) and graphene oxide (GO) nanoparticles are developed. The synergistic effect of these two materials significantly enhances both ultimate strain (250%), reversible rotation (9700°), and the fracture energy (38.8 ± 0.8 J m(-2) ) in the hybrid network. Furthermore, improved electrical signal propagation and subsequent contraction of the muscles connected by hybrid hydrogels are observed in ex vivo tests.

Indexed as

ElasticityElectric ConductivityEngineeringGraphiteHumansHydrogelsModels, MolecularMolecular ConformationOxidesTensile StrengthTropoelastinGraphiteHydrogelsOxidesTropoelastincardiac tissue engineeringelasticitygraphene oxideshydrogelstropoelastins

Identifiers

PMID26551969
PMCPMC4863466

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.