ArticleInternational journal of surgery case reports2015
A case of Menetrier's disease without Helicobacter pylori or hypoalbuminemia.
Article in International journal of surgery case reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 17 citations in OpenAlex.
- Unusual Suspect: Ménétrier Disease Presents as Gastric Outlet Obstruction in a Toddler.ACG case reports journal · 2025Article
- Article
- Clinical and Radiological Features of Menetrier's Disease: A Case Report and Review of the Literature.Cureus · 2023Article
- Abnormal Levels of Pepsinogen I and Gastrin 17 in a case of Ménétrier Disease.Acta bio-medica : Atenei Parmensis · 2021Article
- Diagnosis and Management of Ménétrier Disease in Children: A Case Series Review.Pediatric gastroenterology, hepatology & nutrition · 2021Article
- A Misdiagnosed Case of Hypertrophic Gastropathy.Case reports in pathology · 2020Article
- Total gastrectomy for the treatment of Menetrier's disease persistent to medical therapy: A case report.International journal of surgery case reports · 2020Article
- A case report of diffuse hyperplastic gastropathy with multiple polypoid formations in a patient with pernicious anemia, Helicobacter pylori infection, hypergastrinemia and hypoalbuminaemia: Do not forget of Ménétrier's disease.International journal of surgery case reports · 2020Article
- A Rare Etiology of Abnormally Large Gastric Folds: Menetrier's Disease.Case reports in gastrointestinal medicine · 2019Article
- Protein losing enteropathy: comprehensive review of the mechanistic association with clinical and subclinical disease states.Clinical and experimental gastroenterology · 2017Review
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionMenetrier's disease is a rare premalignant hypertrophic gastropathy. It is characterized by huge gastric mucosal folds, peripheral edema due to protein loss and upper GIT symptoms such as epigastric pain, discomfort, nausea and vomiting. PRESENTATION OF CASE: Female patient 35 years old complaining of severe epigastric pain, dyspepsia, nausea and vomiting for 1 year. Upper GIT endoscopy and CT scan revealed thickening of gastric mucosa. Endoscopic biopsy was non-specific but showed moderate grade dysplasia and no Helicobacter pylori infection. All laboratory investigations were within normal including serum albumin. She underwent total gastrectomy with marked postoperative improvement of symptoms after recovery. Postoperative pathology revealed gastric fovular hyperplasia and glandular atrophy which are diagnostic for Menetrier's disease. DISCUSSION: the preoperative diagnosis of Menetrier's disease in this case was challenged by its unusual features. There were neither H. pylori nor hypoalbuminemia. Literature review showed similarcases which can raise the suspicion of the presence of an undescribed subtype of the disease.
conclusionMenetrier's disease should be suspected in cases of upper GIT symptoms and hypertrophied gastric mucosa with or without H. pylori or hypoalbuminemia. The preoperative diagnosis could not be confirmed unless a whole mucosal thickness biopsy is performed. Surgical management is a good option when medical treatment fails to relieve the symptoms and erase the risk of malignancy.
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