ArticleJournal of occupational and environmental hygiene2015
Advances in Inhalation Dosimetry Models and Methods for Occupational Risk Assessment and Exposure Limit Derivation.
Article in Journal of occupational and environmental hygiene, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 35 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 2 syntheses or guidelines pooled it, 110 citations in OpenAlex.
- The gut-brain axis mediates precocious puberty induced by environmentally relevant low-dose endocrine-disrupting chemical mixtures.Frontiers in endocrinology · 2025Pooled it
- Welding Fumes, a Risk Factor for Lung Diseases.International journal of environmental research and public health · 2020Pooled it
- An Integrated AIVIVE-PBPK-QIVIVE Framework with HTTK Validation for Probabilistic Risk Assessment of Neodymium Nitrate.Chemical research in toxicology · 2026Article
- Airborne PMInternational journal of molecular sciences · 2025Article
- Formaldehyde and asthma: a plausibility?Archives of toxicology · 2025Review
- Intra-Continental Transport of Western Wildfire Smoke Heightens Health Risks Across North America.International journal of environmental research and public health · 2025Article
- Evaluation of a non-animal toolbox informed by adverse outcome pathways for human inhalation safety.Frontiers in toxicology · 2025Article
- Methodological steps forward in toxicological in vitro screening of mineral wools in primary rat alveolar macrophages and normal rat mesothelial NRM2 cells.Archives of toxicology · 2024Article
- Benchmark dose determining airborne crystalline silica particles based on A549 lung-cell line survival in an in vitro study.Scientific reports · 2024Article
- New approach methodologies (NAMs) for theFrontiers in toxicology · 2024Review
- Impact of Natural-Based Viscosity Modifiers of Inhalation Drugs on the Dynamic Surface Properties of the Pulmonary Surfactant.Materials (Basel, Switzerland) · 2023Article
- Towards health-based nano reference values (HNRVs) for occupational exposure: Recommendations from an expert panel.NanoImpact · 2022Article
- Human exposure to metals in consumer-focused fused filament fabrication (FFF)/ 3D printing processes.The Science of the total environment · 2022Review
- Article
- Occupational Exposure to Formaldehyde and Cancer Risk Assessment in an Anatomy Laboratory.International journal of environmental research and public health · 2021Article
- Emerging Technologies for In Vitro Inhalation Toxicology.Advanced healthcare materials · 2021Review
- New Approach Methodology for Assessing Inhalation Risks of a Contact Respiratory Cytotoxicant: Computational Fluid Dynamics-Based Aerosol Dosimetry Modeling for Cross-Species and In Vitro Comparisons.Toxicological sciences : an official journal of the Society of Toxicology · 2021Article
- Estimation of the Inhaled Dose of Pollutants in Different Micro-Environments: A Systematic Review of the Literature.Toxics · 2021Review
- Review and Evaluation of the Potential Health Effects of Oxidic Nickel Nanoparticles.Nanomaterials (Basel, Switzerland) · 2021Review
- Gas sensors based on mass-sensitive transducers. Part 2: Improving the sensors towards practical application.Analytical and bioanalytical chemistry · 2020Review
Corrections and comments
- Erratum issuedCorrigendum.2018
Authors and funding
4 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The purpose of this article is to provide an overview and practical guide to occupational health professionals concerning the derivation and use of dose estimates in risk assessment for development of occupational exposure limits (OELs) for inhaled substances. Dosimetry is the study and practice of measuring or estimating the internal dose of a substance in individuals or a population. Dosimetry thus provides an essential link to understanding the relationship between an external exposure and a biological response. Use of dosimetry principles and tools can improve the accuracy of risk assessment, and reduce the uncertainty, by providing reliable estimates of the internal dose at the target tissue. This is accomplished through specific measurement data or predictive models, when available, or the use of basic dosimetry principles for broad classes of materials. Accurate dose estimation is essential not only for dose-response assessment, but also for interspecies extrapolation and for risk characterization at given exposures. Inhalation dosimetry is the focus of this paper since it is a major route of exposure in the workplace. Practical examples of dose estimation and OEL derivation are provided for inhaled gases and particulates.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.