Evidence map›Paper›PMID 26550492›Full record

ReviewJournal of pregnancy2015

AngiomiRs: Potential Biomarkers of Pregnancy's Vascular Pathologies.

Laura María Rodríguez Santa, Laura Yuriko González Teshima, Jose Vicente Forero Forero, Andres Orlando Castillo Giraldo

Open access · goldAbstract readReview
In one paragraph

Review in Journal of pregnancy, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. MicroRNAs: New Players in the Pathobiology of Preeclampsia.Frontiers in cardiovascular medicine · 2017
    Review
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Laura María Rodríguez SantaBasic Sciences School, Health Faculty, Universidad del Valle, Sede San Fernando, Calle 4B No. 36-00, 760043 Cali, Valle del Cauca, Colombia.
Laura Yuriko González TeshimaBasic Sciences School, Health Faculty, Universidad del Valle, Sede San Fernando, Calle 4B No. 36-00, 760043 Cali, Valle del Cauca, Colombia.
Jose Vicente Forero ForeroBasic Sciences School, Health Faculty, Universidad del Valle, Sede San Fernando, Calle 4B No. 36-00, 760043 Cali, Valle del Cauca, Colombia.
Andres Orlando Castillo GiraldoBasic Sciences School, Health Faculty, Universidad del Valle, Sede San Fernando, Calle 4B No. 36-00, 760043 Cali, Valle del Cauca, Colombia ; Department of Biological Sciences, Natural Sciences Faculty, Universidad ICESI, Calle 18 No. 122-135, 760031 Cali, Valle del Cauca, Colombia.
Universidad del Valle · CO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, microRNAs (miRNAs) have been the focus of research for their role in posttranscriptional regulation and as potential biomarkers of risk for disease development. Their identification in specific physiological processes, like angiogenesis, a key pathway in placental vascular development in pregnancy, suggests an important role of miRNAs that regulate angiogenesis (angiomiRs). Many complications of pregnancy have in common placental vascular alterations, involving an imbalance in the angiogenesis process in the development of conditions such as preeclampsia, intrauterine growth restriction, and gestational diabetes, complications with the highest rates of morbimortality in pregnancy. Many studies have identified angiomiRs with differential expression profiles in each of these diseases; however, this evidence requires further studies focused on evaluating their potential as biomarkers of risk for the angiomiRs detected, to establish correlations between placental tissue and serum/plasma expression profiles. Therefore, the objective of this review is to highlight the best angiomiRs detected in placental tissue and serum/plasma in each of these three pathologies to show the current data available for potential biomarkers and to propose future research strategies on this topic.

Indexed as

Early DiagnosisBiomarkersDiabetes, GestationalFemaleFetal Growth RetardationHumansMicroRNAsNeovascularization, PathologicPlacentaPre-EclampsiaPregnancyPregnancy ComplicationsBiomarkersMicroRNAs

Identifiers

PMID26550492
PMCPMC4621355
OpenAlexW1940434377

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.