Evidence map›Paper›PMID 26550467›Full record

ArticleInvestigative genetics2015

Early modern human dispersal from Africa: genomic evidence for multiple waves of migration.

Francesca Tassi, Silvia Ghirotto, Massimo Mezzavilla, Sibelle Torres Vilaça, Lisa De Santi, Guido Barbujani

Abstract read
In one paragraph

Article in Investigative genetics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
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25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

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  14. Evolution, Prehistory and Vitamin D.International journal of environmental research and public health · 2020
    Review
  15. Circuit-theory applications to connectivity science and conservation.Conservation biology : the journal of the Society for Conservation Biology · 2019
    Review
  16. Article
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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

6 authors.

Francesca Tassi *Department of Life Sciences and Biotechnologies, University of Ferrara, Ferrara, Italy.
Silvia Ghirotto *Department of Life Sciences and Biotechnologies, University of Ferrara, Ferrara, Italy.
Massimo MezzavillaInstitute for Maternal and Child Health-IRCCS "BurloGarofolo", University of Trieste, Trieste, Italy.
Sibelle Torres VilaçaDepartment of Life Sciences and Biotechnologies, University of Ferrara, Ferrara, Italy.
Lisa De SantiDepartment of Life Sciences and Biotechnologies, University of Ferrara, Ferrara, Italy.
Guido BarbujaniDepartment of Life Sciences and Biotechnologies, University of Ferrara, Ferrara, Italy.ORCID 0000-0001-7854-6669

Funding

European Research Council 295733
6 · The paper itself

Abstract

backgroundAnthropological and genetic data agree in indicating the African continent as the main place of origin for anatomically modern humans. However, it is unclear whether early modern humans left Africa through a single, major process, dispersing simultaneously over Asia and Europe, or in two main waves, first through the Arab Peninsula into southern Asia and Oceania, and later through a northern route crossing the Levant.

resultsHere, we show that accurate genomic estimates of the divergence times between European and African populations are more recent than those between Australo-Melanesia and Africa and incompatible with the effects of a single dispersal. This difference cannot possibly be accounted for by the effects of either hybridization with archaic human forms in Australo-Melanesia or back migration from Europe into Africa. Furthermore, in several populations of Asia we found evidence for relatively recent genetic admixture events, which could have obscured the signatures of the earliest processes.

conclusionsWe conclude that the hypothesis of a single major human dispersal from Africa appears hardly compatible with the observed historical and geographical patterns of genome diversity and that Australo-Melanesian populations seem still to retain a genomic signature of a more ancient divergence from Africa.

Indexed as

AdmixtureEvolutionary divergenceHuman demographic historyLinkage disequilibriumMigrationPopulation structure

Identifiers

PMID26550467
PMCPMC4636834

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.