Evidence map›Paper›PMID 26550381›Full record

ArticleInternational journal of clinical and experimental medicine2015

Effects of epidural analgesia with different concentrations of bupivacaine plus fentanyl on pain in patients undergoing thoracic surgery.

Hao Li, Baosheng Wang, Fumei Wang, Zan Xu, Naibao Zhou, Xiuqin Wang, Kaiguo Wang

Abstract read
In one paragraph

Article in International journal of clinical and experimental medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Hao LiDepartment of Anesthesiology, Shandong Cancer Hospital & Institute No. 440 Jiyan Road, Jinan 250117, Shandong, China.
Baosheng WangDepartment of Anesthesiology, Shandong Cancer Hospital & Institute No. 440 Jiyan Road, Jinan 250117, Shandong, China.
Fumei WangDepartment of Anesthesiology, Shandong Cancer Hospital & Institute No. 440 Jiyan Road, Jinan 250117, Shandong, China.
Zan XuDepartment of Anesthesiology, Shandong Cancer Hospital & Institute No. 440 Jiyan Road, Jinan 250117, Shandong, China.
Naibao ZhouDepartment of Anesthesiology, Shandong Cancer Hospital & Institute No. 440 Jiyan Road, Jinan 250117, Shandong, China.
Xiuqin WangDepartment of Anesthesiology, Shandong Cancer Hospital & Institute No. 440 Jiyan Road, Jinan 250117, Shandong, China.
Kaiguo WangDepartment of Anesthesiology, Shandong Cancer Hospital & Institute No. 440 Jiyan Road, Jinan 250117, Shandong, China.
Shandong Tumor Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate and compared the efficacy and safety of epidural analgesia with different concentrations of bupivacaine plus fentanyl on pain in patients undergoing thoracic surgery.

methods120 cases undergoing elective thoracic surgery were randomly divided into A, B, C and D four groups each with 30 cases, and they were treated with 0.25% (A group), 0.375% (B group), 0.50% (C group) and 0.75% (D group) bupivacaine plus fentanyl 0.4 mg. The pain conditions postoperative 4 h, 8 h, 12 h, 24 h and 48 h were evaluated by visual analogue scale (VAS). The PCA pressing numbers and incidence of adverse reactions were compared between the four groups.

resultsBy postoperative 4 h, the VAS in D group were obviously lower than those in the other three groups (P all <0.05), and the other three groups showed no significances (P>0.05). However, the four groups showed no significant differences in VAS by postoperative 8 h, 12 h, 24 h and 48 h (P all >0.05). The incidences of respiratory depression in C and D groups were markedly higher than those in A and B groups (P all <0.05).

conclusions0.25%~0.375% bupivacaine plus fentanyl 0.4 mg using in epidural analgesia in patients undergoing thoracic surgery can lead to safe and effective analgesic effect.

Indexed as

bupivacaineEpidural analgesiapatient-controlled analgesiarespiratory depression

Identifiers

PMID26550381
PMCPMC4613066
OpenAlexW2191331359

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.