ArticleInternational journal of clinical and experimental medicine2015
Association of CCND1 gene polymorphism with cervical cancer susceptibility in Caucasian population: a meta-analysis.
Article in International journal of clinical and experimental medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.
- Association betweenBioscience reports · 2018Pooled it
- Aberrant Cyclin D1 splicing in cancer: from molecular mechanism to therapeutic modulation.Cell death & disease · 2023Review
- Cyclin D1 G870A polymorphism: Association with uterine leiomyoma risk andBiomedical reports · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo study G870A polymorphism in CCND1 gene and the risk of cervical cancer susceptibility in Caucasian population by meta-analysis.
methodsSearch the correlative study of G870A polymorphism in CCND1 gene and cervical cancer susceptibility in PubMed and EMBASE database, and extract the reference data according to the including criteria. We used RevMan 5.2 software to merge the OR value and 95% confidence interval and to perform meta-analysis.
resultsFive case-control studies were enrolled into the analysis, including 1665 patients with cervical cancer and 2511 healthy people as control. It was revealed by meta-analysis that, in the Caucasian population, there was no significant correlation between G870A polymorphism in CCND1 gene and the risk of cervical cancer (G allele vs. A: OR = 1.01, 95% CI = 0.80-1.27, P = 0.95; AA vs. GA + GG: OR = 1.13, 95% CI = 0.98-1.30, P = 0.10; (GA + AA) vs. GG: OR = 1.15, 95% CI = 0.72-1.85, P = 0.55).
conclusionG870A polymorphism in CCND1 gene may be uncorrelated with the development of cervical cancer in Caucasian population.
Indexed as
Identifiers
26550218PMC4612903W2195584672What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.