ArticleInternational journal of clinical and experimental medicine2015
Association between IL-17F rs763780 polymorphism and susceptibility of asthma: a meta-analysis.
Article in International journal of clinical and experimental medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- The IL17F His161Arg polymorphism, a potential risk locus for psoriasis, increases serum levels of interleukin-17F in an Asian population.Scientific reports · 2019Trial
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Published data on the association between interleukin-17F (IL-17F) rs763780 polymorphism and asthma susceptibility are inconclusive. To derive a more precise estimation of this association, a meta-analysis was performed. A literature search was conducted in PubMed, Web of Science, Elsevier, Wanfang, and China National Knowledge Infrastructure (CNKI) databases to identify eligible studies. The pooled odds ratios (ORs) and corresponding 95% confidence intervals (CIs) were used to calculate the strength of association. Sensitivity analysis was performed to evaluate the influence of individual studies on the overall effect estimates and funnel plots were inspected for indication of publication bias. Seven studies with a total of 4200 subjects were finally identified. Overall, we found no significant association between IL-17F rs763780 polymorphism and asthma susceptibility (G vs. A: OR = 1.08, 95% CI = 0.81-1.44, P = 0.62; GA vs. AA: OR = 1.11, 95% CI = 0.84-1.47, P = 0.47; GG + GA vs. AA: OR = 1.07, 95% CI = 0.79-1.44, P = 0.65). After categorizing studies into different subgroups on the basis of ethnicity and age, there remained no significant association (all P > 0.05). Sensitivity analysis demonstrated the stability of our results and publication bias was not evident. The present meta-analysis, combining all currently available data, suggests that IL-17F rs763780 polymorphism is not associated with the susceptibility of asthma.
Indexed as
Identifiers
26550210PMC4612895What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.