ReviewJournal of ultrasound2015
Acute acalculous cholecystitis and cardiovascular disease: a land of confusion.
Review in Journal of ultrasound, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 31 citations in OpenAlex.
- Abdominal Pain as the First Presentation of Severe Heart Failure With Reduced Ejection Fraction and Left Ventricular Thrombus in a Young Asymptomatic Patient: A Diagnostic Interception.Clinical case reports · 2026Article
- Gallstones and acute cholecystitis in CKD and dialysis: an underrecognized biliary burden in nephrology.Clinical and experimental nephrology · 2026Review
- Optimizing infection management after cardiac arrest: addressing diagnostic uncertainty and therapeutic dilemmas-a narrative review.Journal of intensive care · 2026Review
- When the Gallbladder Follows The Right Heart: A case report of cardio-biliary syndrome in pulmonary arterial hypertension.Radiology case reports · 2026Article
- Acalculous Cholecystitis: The Unexpected Mask of De Novo Heart Failure.Clinical case reports · 2025Article
- Thickened Gallbladder Wall, Abdominal Pain, and Fever: A Rare Presentation of Dengue in Rural Australia.Cureus · 2024Article
- Review
- Rare or Overlooked Cases of Acute Acalculous Cholecystitis in Young Patients with Central Nervous System Lesion.Healthcare (Basel, Switzerland) · 2023Article
- Coronary Artery Disease and Gallbladder Inflammatory Pseudopolyps.Diagnostics (Basel, Switzerland) · 2022Article
- Percutaneous cholecystostomy as a definitive treatment for moderate and severe acute acalculous cholecystitis: a retrospective observational study.BMC surgery · 2021Observational
- Imaging of gallbladder metastasis.Insights into imaging · 2021Review
- Gallbladder polyps ultrasound: what the sonographer needs to know.Journal of ultrasound · 2021Review
- Acute cholecystitis as a rare and overlooked complication in stroke patients: A retrospective monocentric study.Medicine · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acute acalculous cholecystitis (AAC) can be defined as acute inflammatory disease of the gallbladder without evidence of gallstones. The first case was reported in 1844 by Duncan et al.; however, some cases may have been missed previously in view of the complexity of the diagnosis. Several risk factors have been identified, and cardiovascular disease (CVD), in view of its multiple mechanisms of action, seems to play a key role. Atypical clinical onset, paucity of symptoms, overlap with comorbidities, and lack of robust, controlled trials result often in under or misdiagnosed cases. Moreover, laboratory results may be negative or not specific in the late stage of the disease, when a surgical treatment cannot be longer helpful if complications arise. A rapid diagnosis is therefore essential to achieve a prompt treatment and to avoid further clinical deterioration. In this short review, we would present the current evidence regarding epidemiology, pathophysiology, and clinical presentation of the complex relation between AAC and CVD. Then, we fully emphasize the role of ultrasound to achieve an early diagnosis and an appropriate treatment in suspected cases, reducing mortality and complications rates.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.