Evidence map›Paper›PMID 26549801›Full record

ArticleCellular & molecular immunology2017

Magnesium ion influx reduces neuroinflammation in Aβ precursor protein/Presenilin 1 transgenic mice by suppressing the expression of interleukin-1β.

Pu Wang, Xin Yu, Pei-Pei Guan, Jing-Wen Guo, Yue Wang, Yan Zhang, Hang Zhao, Zhan-You Wang

Abstract read
In one paragraph

Article in Cellular & molecular immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 2 pooled it
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 2 syntheses or guidelines pooled it, 64 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Magnesium: Hype and Health Benefits.Current nutrition reports · 2026
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Mechanism of Metal Complexes in Alzheimer's Disease.International journal of molecular sciences · 2024
    Review
  12. Review
  13. Article
  14. Review
  15. Article
  16. Review
  17. Magnesium (MgCurrent pharmaceutical design · 2024
    Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Pu WangCollege of Life and Health Sciences, Northeastern University, Shenyang, P. R. China.
Xin YuCollege of Life and Health Sciences, Northeastern University, Shenyang, P. R. China.
Pei-Pei GuanCollege of Life and Health Sciences, Northeastern University, Shenyang, P. R. China.
Jing-Wen GuoCollege of Life and Health Sciences, Northeastern University, Shenyang, P. R. China.
Yue WangCollege of Life and Health Sciences, Northeastern University, Shenyang, P. R. China.
Yan ZhangCollege of Life and Health Sciences, Northeastern University, Shenyang, P. R. China.
Hang ZhaoCollege of Life and Health Sciences, Northeastern University, Shenyang, P. R. China.
Zhan-You WangCollege of Life and Health Sciences, Northeastern University, Shenyang, P. R. China.
Northeastern University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alzheimer's disease (AD) has been associated with magnesium ion (Mg

Indexed as

Alzheimer DiseaseAmyloid beta-PeptidesAmyloid beta-Protein PrecursorAnimalsBrainCells, CulturedDisease Models, AnimalGlioblastomaHumansInflammationInterleukin-1betaMagnesiumMaleMiceMice, Inbred C57BLMice, TransgenicAmyloid beta-PeptidesAmyloid beta-Protein PrecursorAPP protein, humanInterleukin-1betaMagnesiumPresenilin-1

Identifiers

PMID26549801
PMCPMC5423087
OpenAlexW2180417073

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.