ArticleScientific reports2015
Convergent evolution of marine mammals is associated with distinct substitutions in common genes.
Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 43 citations in OpenAlex.
- The genetic foundations of convergent traits.Nature reviews. Genetics · 2026Review
- The genomic basis of independent marine transitions in turtles: convergent episodic adaptation and demographic shifts.Molecular biology and evolution · 2026Article
- Genomic basis of adaptation to cardiac glycosides in three insect orders.Frontiers in genetics · 2026Article
- Phylogenomic Approaches to Study Adaptive Evolution in Mammals: From Aging to Aquatic Lifestyles.Annual review of genetics · 2025Review
- From Trees to Traits: A Review of Advances in PhyloG2P Methods and Future Directions.Genome biology and evolution · 2025Review
- Molecular characterization of positively selected genes contributing aquatic adaptation in marine mammals.Genes & genomics · 2024Article
- Breathing Air and Living Underwater: Molecular Evolution of Genes Related to Antioxidant Response in Cetaceans and Pinnipeds.Journal of molecular evolution · 2024Article
- Adaptive strategies of aquatic mammals: Exploring the role of the HIF pathway and hypoxia tolerance.Genetics and molecular biology · 2024Article
- Genomic Divergence and the Evolution of Ecotypes in Bottlenose Dolphins (Genus Tursiops).Genome biology and evolution · 2023Article
- Molecular mechanisms of adaptive evolution in wild animals and plants.Science China. Life sciences · 2023Review
- Article
- Genomic Evidence for Convergent Molecular Adaptation in Electric Fishes.Genome biology and evolution · 2021Article
- An Indo-Pacific Humpback Dolphin Genome Reveals Insights into Chromosome Evolution and the Demography of a Vulnerable Species.iScience · 2020Article
- Evidence of Echolocation in the Common Shrew from Molecular Convergence with Other Echolocating Mammals.Zoological studies · 2020Article
- Convergent degeneration of olfactory receptor gene repertoires in marine mammals.BMC genomics · 2019Article
- Deciphering the evolutionary signatures of pinnipeds using novel genome sequences: The first genomes of Phoca largha, Callorhinus ursinus, and Eumetopias jubatus.Scientific reports · 2018Article
- Limited Evidence for Parallel Molecular Adaptations Associated with the Subterranean Niche in Mammals: A Comparative Study of Three Superorders.Molecular biology and evolution · 2018Article
- The Antarctic sea ice alga Chlamydomonas sp. ICE-L provides insights into adaptive patterns of chloroplast evolution.BMC plant biology · 2018Article
- Molecular Footprints of Aquatic Adaptation Including Bone Mass Changes in Cetaceans.Genome biology and evolution · 2018Article
- Evolutionary changes of Hox genes and relevant regulatory factors provide novel insights into mammalian morphological modifications.Integrative zoology · 2018Article
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Phenotypic convergence is thought to be driven by parallel substitutions coupled with natural selection at the sequence level. Multiple independent evolutionary transitions of mammals to an aquatic environment offer an opportunity to test this thesis. Here, whole genome alignment of coding sequences identified widespread parallel amino acid substitutions in marine mammals; however, the majority of these changes were not unique to these animals. Conversely, we report that candidate aquatic adaptation genes, identified by signatures of likelihood convergence and/or elevated ratio of nonsynonymous to synonymous nucleotide substitution rate, are characterized by very few parallel substitutions and exhibit distinct sequence changes in each group. Moreover, no significant positive correlation was found between likelihood convergence and positive selection in all three marine lineages. These results suggest that convergence in protein coding genes associated with aquatic lifestyle is mainly characterized by independent substitutions and relaxed negative selection.
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