Evidence map›Paper›PMID 26547129›Full record

SynthesisMedical science monitor : international medical journal of experimental and clinical research2015

Association of Vitamin E Intake with Reduced Risk of Kidney Cancer: A Meta-Analysis of Observational Studies.

Chongxing Shen, Ying Huang, Shanhong Yi, Zhenqiang Fang, Longkun Li

Open access · bronzeAbstract readMeta-Analysis
In one paragraph

Synthesis in Medical science monitor : international medical journal of experimental and clinical research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 4 pooled it
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 4 syntheses or guidelines pooled it, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Chongxing ShenDepartment of Urology, Second Affiliated Hospital, Third Military Medical University, Chongqing, China (mainland).
Ying HuangDepartment of Ultrasound, Second Affiliated Hospital, Third Military Medical University, Chongqing, China (mainland).
Shanhong YiDepartment of Urology, Second Affiliated Hospital, Third Military Medical University, Chongqing, China (mainland).
Zhenqiang FangDepartment of Urology, Second Affiliated Hospital, Third Military Medical University, Chongqing, China (mainland).
Longkun LiDepartment of Urology, Second Affiliated Hospital, Third Military Medical University, Chongqing, China (mainland).
Army Medical University · CNXinqiao Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSeveral observational studies suggested that vitamin E intake is related to the risk of kidney cancer; however, the results of published studies are inconsistent. MATERIAL AND

methodsA meta-analysis was performed to assess the relationship between vitamin E intake and the risk of kidney cancer by searching PubMed and Medline through August 2015. We computed pooled relative risks (RR) and 95%CI of kidney cancer for the highest versus lowest level of vitamin E intake.

resultsA total of 13 observational studies (7 case-control and 6 cohort) were included. The pooled RR (95%CI) of kidney cancer for the highest vs. the lowest level of vitamin E intake was 0.81 (0.69-0.94). In subgroup-analysis, this study found an inverse relationship between vitamin E intake and kidney cancer risk, which was not significantly modified by study design, study population, or sex distribution except in the cohort studies.

conclusionsResults of the present study suggest an inverse relationship between vitamin E intake and kidney cancer risk. However, additional well designed cohort studies and randomized controlled trials that focus on the relationship between vitamin E intake and kidney cancer risk are needed.

Indexed as

AdultAgedDietFemaleHumansKidney NeoplasmsMaleMiddle AgedObservational Studies as TopicRandomized Controlled Trials as TopicRisk FactorsSex FactorsVitamin EVitamin E

Identifiers

PMID26547129
PMCPMC4644018
OpenAlexW2103429559

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.