Evidence map›Paper›PMID 26546518›Full record

ArticleNucleic acids research2016

The Transporter Classification Database (TCDB): recent advances.

Milton H Saier, Vamsee S Reddy, Brian V Tsu, Muhammad Saad Ahmed, Chun Li, Gabriel Moreno-Hagelsieb

Abstract read
In one paragraph

Article in Nucleic acids research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 391 papers.

0numbers the graph read from it
0cells of the map it votes in
391citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

391 citing papers in PubMed.

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  13. Genomic insights intoFrontiers in veterinary science · 2026
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  14. Genetic Basis of Multiple Antibiotic Resistance of PathogenicInternational journal of molecular sciences · 2025
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  15. Root growth promotion bybioRxiv : the preprint server for biology · 2025
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  16. pH-dependent regulation in SLC38A9.bioRxiv : the preprint server for biology · 2025
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331 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Milton H SaierDepartment of Molecular Biology, University of California at San Diego, La Jolla, CA 92093-0116, USA msaier@ucsd.edu.
Vamsee S ReddyDepartment of Molecular Biology, University of California at San Diego, La Jolla, CA 92093-0116, USA Department of Medical Sciences, Boston University School of Medicine, 72 E Concord St., Boston, MA 02118, USA.
Brian V TsuDepartment of Molecular Biology, University of California at San Diego, La Jolla, CA 92093-0116, USA.
Muhammad Saad AhmedDepartment of Biological Engineering, School of Life Sciences, Beijing Institute of Technology, Beijing 100081, People's Republic of China.
Chun LiDepartment of Biological Engineering, School of Life Sciences, Beijing Institute of Technology, Beijing 100081, People's Republic of China.
Gabriel Moreno-HagelsiebDepartment of Molecular Biology, University of California at San Diego, La Jolla, CA 92093-0116, USA Department of Biology, Wilfrid Laurier University, 75 University Ave W, Waterloo, ON, Canada N2L 3C5.

Funding

The Transporter Classification Database (TCDB)R01GM077402 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SAIER, MILTON H. · 2006 to 2021
$4.7M
NIGMS NIH HHS GM 077402NIGMS NIH HHS GM077402NIGMS NIH HHS R01 GM077402
6 · The paper itself

Abstract

The Transporter Classification Database (TCDB; http://www.tcdb.org) is a freely accessible reference database for transport protein research, which provides structural, functional, mechanistic, evolutionary and disease/medical information about transporters from organisms of all types. TCDB is the only transport protein classification database adopted by the International Union of Biochemistry and Molecular Biology (IUBMB). It consists of more than 10,000 non-redundant transport systems with more than 11 000 reference citations, classified into over 1000 transporter families. Transporters in TCDB can be single or multi-component systems, categorized in a functional/phylogenetic hierarchical system of classes, subclasses, families, subfamilies and transport systems. TCDB also includes updated software designed to analyze the distinctive features of transport proteins, extending its usefulness. Here we present a comprehensive update of the database contents and features and summarize recent discoveries recorded in TCDB.

Indexed as

Databases, ProteinMembrane Transport ProteinsSequence Analysis, ProteinMembrane Transport Proteins

Identifiers

PMID26546518
PMCPMC4702804

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.