ReviewExperimental cell research2016
Problems in biology with many scales of length: Cell-cell adhesion and cell jamming in collective cellular migration.
Review in Experimental cell research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
13 citing papers in PubMed, 33 citations in OpenAlex.
- Mechano-metabolic feedback connects tissue fluidity to mitochondrial DNA-dependent immunity in breast cancer.Nature communications · 2026Article
- Epithelial Layer Fluidization by Curvature-Induced Unjamming.Physical review letters · 2025Article
- Genomic signatures of the unjamming transition in compressed human bronchial epithelial cells.Science advances · 2021Article
- Deep neural net tracking of human pluripotent stem cells reveals intrinsic behaviors directing morphogenesis.Stem cell reports · 2021Article
- Irradiation Induces Epithelial Cell Unjamming.Frontiers in cell and developmental biology · 2020Article
- Why does epithelia display heterogeneity? Bridging physical and biological concepts.Biophysical reviews · 2019Article
- The migration and fusion events related to ROCK activity strongly influence the morphology of chicken embryo intestinal organoids.Protoplasma · 2019Article
- Jamming state transition and collective cell migration.Journal of biological engineering · 2019Article
- Biomechanics of Collective Cell Migration in Cancer Progression: Experimental and Computational Methods.ACS biomaterials science & engineering · 2019Article
- Coherent Timescales and Mechanical Structure of Multicellular Aggregates.Biophysical journal · 2018Article
- Successive relaxation cycles during long-time cell aggregate rounding after uni-axial compression.Journal of biological physics · 2017Article
- Cancer cells: Stemness shaped by curvature.Nature materials · 2016Article
- Traction Force Microscopy for Noninvasive Imaging of Cell Forces.Advances in experimental medicine and biologyReview
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
As do all things in biology, cell mechanosensation, adhesion and migration begin at the scale of the molecule. Collections of molecules assemble to comprise microscale objects such as adhesions, organelles and cells. And collections of cells in turn assemble to comprise macroscale tissues. From the points of view of mechanism and causality, events at the molecular scale are seen most often as being the most upstream and, therefore, the most fundamental and the most important. In certain collective systems, by contrast, events at many scales of length conspire to make contributions of equal importance, and even interact directly and strongly across disparate scales. Here we highlight recent examples in cellular mechanosensing and collective cellular migration where physics at some scale bigger than the cell but smaller than the tissue - the mesoscale - becomes the missing link that is required to tie together findings that might otherwise seem counterintuitive or even unpredictable. These examples, taken together, establish that the phenotypes and the underlying physics of collective cellular migration are far richer than previously anticipated.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.