ArticlePlant molecular biology2016
Reassessment of an Arabidopsis cell wall invertase inhibitor AtCIF1 reveals its role in seed germination and early seedling growth.
Article in Plant molecular biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 44 citations in OpenAlex.
- Nuclear SnRK1 Activity Delays Clubroot Development in Arabidopsis by Reducing Sink Strength.Plant, cell & environment · 2026Article
- Genome-Wide Identification of Pineapple AcINH Genes and Functional Characterization ofPlants (Basel, Switzerland) · 2026Article
- Cell Wall Invertases from Maternal Tissues Modulate Sucrose Flux in Apoplastic Pathways During Rice Anther and Seed Development.International journal of molecular sciences · 2024Article
- Genome-Wide Identification and Expression Patterns of Cucumber Invertases and Their Inhibitor Genes.International journal of molecular sciences · 2023Article
- How pollen tubes fight for food: the impact of sucrose carriers and invertases ofFrontiers in plant science · 2023Article
- Combining QTL mapping and gene co-expression network analysis for prediction of candidate genes and molecular network related to yield in wheat.BMC plant biology · 2022Article
- Functional characterization of a cell wall invertase inhibitor StInvInh1 revealed its involvement in potato microtuber sizeFrontiers in plant science · 2022Article
- The Plant Invertase/Pectin Methylesterase Inhibitor Superfamily.Frontiers in plant science · 2022Review
- Article
- Functional disruption of cell wall invertase inhibitor by genome editing increases sugar content of tomato fruit without decrease fruit weight.Scientific reports · 2021Article
- Melatonin Modulates Plant Tolerance to Heavy Metal Stress: Morphological Responses to Molecular Mechanisms.International journal of molecular sciences · 2021Review
- StRAP2.3, an ERF-VII transcription factor, directly activates StInvInh2 to enhance cold-induced sweetening resistance in potato.Horticulture research · 2021Article
- Cell wall/vacuolar inhibitor of fructosidase 1 regulates ABA response and salt tolerance in Arabidopsis.Plant signaling & behavior · 2020Article
- DA-6 promotes germination and seedling establishment from aged soybean seeds by mediating fatty acid metabolism and glycometabolism.Journal of experimental botany · 2019Article
- Functional Characterization of Invertase Inhibitors PtC/VIF1 and 2 Revealed Their Involvements in the Defense Response to Fungal Pathogen inFrontiers in plant science · 2019Article
- Genome-Wide Survey of Invertase Encoding Genes and Functional Characterization of an Extracellular Fungal Pathogen-Responsive Invertase inInternational journal of molecular sciences · 2018Article
- Cell wall invertase activity regulates the expression of the transfer cell-specific transcription factor ZmMRP-1.Planta · 2018Article
- The roles of call wall invertase inhibitor in regulating chilling tolerance in tomato.BMC plant biology · 2017Article
- Relationships between drought, heat and air humidity responses revealed by transcriptome-metabolome co-analysis.BMC plant biology · 2017Article
- Suppression of extracellular invertase inhibitor gene expression improves seed weight in soybean (Glycine max).Journal of experimental botany · 2017Article
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Authors and funding
7 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In higher plants, cell wall invertase (CWI) and vacuolar invertase (VI) are recognized as essential players in sugar metabolism and sugar signaling, thereby affecting source-sink interactions, plant development and responses to environmental cues. CWI and VI expression levels are transcriptionally controlled; however, both enzymes are also subject to posttranslational control by invertase inhibitor proteins. The physiological significances of inhibitor proteins during seed germination and early seedling development are not yet fully understood. Here, we demonstrate that the inhibitor isoform AtCIF1 impacted on seed germination and early seedling growth in Arabidopsis. The primary target of AtCIF1 was shown to be localized to the apoplast after expressing an AtCIF1 YFP-fusion construct in tobacco epidermis and transgenic Arabidopsis root. The analysis of expression patterns showed that AtCWI1 was co-expressed spatiotemporally with AtCIF1 within the early germinating seeds. Seed germination was observed to be accelerated independently of exogenous abscisic acid (ABA) in the AtCIF1 loss-of-function mutant cif1-1. This effect coincided with a drastic increase of CWI activity in cif1-1 mutant seeds by 24 h after the onset of germination, both in vitro and in planta. Accordingly, quantification of sugar content showed that hexose levels were significantly boosted in germinating seeds of the cif1-1 mutant. Further investigation of AtCIF1 overexpressors in Arabidopsis revealed a markedly suppressed CWI activity as well as delayed seed germination. Thus, we conclude that the posttranslational modulation of CWI activity by AtCIF1 helps to orchestrate seed germination and early seedling growth via fine-tuning sucrose hydrolysis and, possibly, sugar signaling.
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