ArticleEnvironmental health : a global access science source2015
Exposure to sub-chronic and long-term particulate air pollution and heart rate variability in an elderly cohort: the Normative Aging Study.
Article in Environmental health : a global access science source, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.
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Who cites it
26 citing papers in PubMed, 2 syntheses or guidelines pooled it, 62 citations in OpenAlex.
- Characteristics of cohort studies of long-term exposure to PMEnvironmental science and pollution research international · 2019Pooled it
- A systematic review of cardiovascular responses associated with ambient black carbon and fine particulate matter.Environment international · 2019Pooled it
- Short-Term Exposure to Ambient Ozone and Fine Particulate Matter and Its Components Increases the Risk of In-Hospital Adverse Outcomes in Patients With Acute Myocardial Infarction: A Time-Stratified Case-Crossover Study.Journal of the American Heart Association · 2026Article
- PM2.5 Induces Cardiomyoblast Senescence via AhR-Mediated Oxidative Stress.Antioxidants (Basel, Switzerland) · 2024Article
- Article
- Epigenetic mechanisms of particulate matter exposure: air pollution and hazards on human health.Frontiers in genetics · 2023Review
- Geomagnetic disturbances reduce heart rate variability in the Normative Aging Study.The Science of the total environment · 2022Article
- The Influence of Environmental Air Pollution on Ventricular Arrhythmias: A Scoping Review.Current cardiology reviews · 2022Article
- A longitudinal analysis of PM2.5 exposure and multimorbidity clusters and accumulation among adults aged 45-85 in China.PLOS global public health · 2022Article
- How Are Epigenetic Modifications Related to Cardiovascular Disease in Older Adults?International journal of molecular sciences · 2021Review
- Key Characteristics of Cardiovascular Toxicants.Environmental health perspectives · 2021Article
- Role of atmospheric particulate matter exposure in COVID-19 and other health risks in human: A review.Environmental research · 2021Review
- Epigenetically mediated electrocardiographic manifestations of sub-chronic exposures to ambient particulate matter air pollution in the Women's Health Initiative and Atherosclerosis Risk in Communities Study.Environmental research · 2021Article
- Comparative validation of an epigenetic mortality risk score with three aging biomarkers for predicting mortality risks among older adult males.International journal of epidemiology · 2019Article
- Synthesis of Harvard Environmental Protection Agency (EPA) Center studies on traffic-related particulate pollution and cardiovascular outcomes in the Greater Boston Area.Journal of the Air & Waste Management Association (1995) · 2019Article
- Impacts of air pollution, temperature, and relative humidity on leukocyte distribution: An epigenetic perspective.Environment international · 2019Article
- Accelerated DNA methylation age and the use of antihypertensive medication among older adults.Aging · 2018Article
- High-resolution mapping of traffic related air pollution with Google street view cars and incidence of cardiovascular events within neighborhoods in Oakland, CA.Environmental health : a global access science source · 2018Article
- [Research on Kalman interpolation prediction model based on micro-region PM2.5 concentration].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2018Article
- Cardiac pathophysiology in response to environmental stress: a current review.Current opinion in physiology · 2018Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundShort-term particulate air pollution exposure is associated with reduced heart rate variability (HRV), a risk factor for cardiovascular morbidity and mortality, in many studies. Associations with sub-chronic or long-term exposures, however, have been sparsely investigated. We evaluated the effect of fine particulate matter (PM2.5) and black carbon (BC) exposures on HRV in an elderly cohort: the Normative Aging Study.
methodsWe measured power in high frequency (HF) and low frequency (LF), standard deviation of normal-to-normal intervals (SDNN), and the LF:HF ratio among participants from the Greater Boston area. Residential BC exposures for 540 men (1161 study visits, 2000-2011) were estimated using a spatio-temporal land use regression model, and residential PM2.5 exposures for 475 men (992 visits, 2003-2011) were modeled using a hybrid satellite based and land-use model. We evaluated associations between moving averages of sub-chronic (3-84 day) and long-term (1 year) pollutant exposure estimates and HRV parameters using linear mixed models.
resultsOne-standard deviation increases in sub-chronic, but not long-term, BC were associated with reduced HF, LF, and SDNN and an increased LF:HF ratio (e.g., 28 day BC: -2.3% HF [95% CI:-4.6, -0.02]). Sub-chronic and long-term PM2.5 showed evidence of relations to an increased LF and LF:HF ratio (e.g., 1 year PM: 21.0% LF:HF [8.6, 34.8]), but not to HF or SDNN, though the effect estimates were very imprecise and mostly spanned the null.
conclusionsWe observed some evidence of a relation between longer-term BC and PM2.5 exposures and changes in HRV in an elderly cohort. While previous studies focused on short-term air pollution exposures, our results suggest that longer-term exposures may influence cardiac autonomic function.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.