Evidence map›Paper›PMID 26546191›Full record

ReviewWorld journal of surgery2016

Quality of Life in Thyroid Cancer is Similar to That of Other Cancers with Worse Survival.

Megan K Applewhite, Benjamin C James, Sharone P Kaplan, Peter Angelos, Edwin L Kaplan, Raymon H Grogan, Briseis Aschebrook-Kilfoy

Abstract readReview
PubMed Publisher
In one paragraph

Review in World journal of surgery, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 83 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
83citing papers in PubMed, 5 pooled it
7.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

83 citing papers in PubMed, 5 syntheses or guidelines pooled it, 187 citations in OpenAlex.

  1. Guideline
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  5. Patient-Reported Quality-of-Life Outcome Measures in the Thyroid Cancer Population.Thyroid : official journal of the American Thyroid Association · 2020
    Pooled it
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  7. Machine learning-based random forest for predicting decreased quality of life in thyroid cancer patients after thyroidectomy.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
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  10. Changes in the frequency of postoperativeSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
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23 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Megan K ApplewhiteEndocrine Surgery Research Group, Department of Surgery, The University of Chicago, 5841 S. Maryland Ave. MC 4052, Chicago, IL, 60637, USA. megan.applewhite@uchospitals.edu.
Benjamin C JamesEndocrine Surgery Research Group, Department of Surgery, The University of Chicago, 5841 S. Maryland Ave. MC 4052, Chicago, IL, 60637, USA.
Sharone P KaplanEndocrine Surgery Research Group, Department of Surgery, The University of Chicago, 5841 S. Maryland Ave. MC 4052, Chicago, IL, 60637, USA.
Peter AngelosEndocrine Surgery Research Group, Department of Surgery, The University of Chicago, 5841 S. Maryland Ave. MC 4052, Chicago, IL, 60637, USA.
Edwin L KaplanEndocrine Surgery Research Group, Department of Surgery, The University of Chicago, 5841 S. Maryland Ave. MC 4052, Chicago, IL, 60637, USA.
Raymon H GroganEndocrine Surgery Research Group, Department of Surgery, The University of Chicago, 5841 S. Maryland Ave. MC 4052, Chicago, IL, 60637, USA.
Briseis Aschebrook-KilfoyDivision of Epidemiology, Department of Health Studies, The University of Chicago, 5841 S. Maryland Ave. MC 2007, N112, Chicago, IL, 60637, USA. brisa@uchicago.edu.
University of Chicago · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe incidence of thyroid cancer is increasing. As such, the number of survivors is rising, and it has been shown that their quality of life (QOL) is worse than expected. Using results from the North American Thyroid Cancer Survivorship Study (NATCSS), a large-scale survivorship study, we aim to compare the QOL of thyroid cancer survivors to the QOL of survivors of other types of cancer.

methodsThe NATCSS assessed QOL overall and in four subcategories: physical, psychological, social, and spiritual well-being using the QOL-Cancer Survivor (QOL-CS) instrument. Studies that used the QOL-CS to evaluate survivors of other types of cancers were compared to the NATCSS findings using two-tailed t tests.

resultsWe compared results from NATCSS to QOL survivorship studies in colon, glioma, breast, and gynecologic cancer. The mean overall QOL in NATCSS was 5.56 (on a scale of 0-10, where 10 is the best). Overall QOL of patients with thyroid cancer was similar to that of patients with colon cancer (mean 5.20, p = 0.13), glioma (mean 5.96, p = 0.23), and gynecologic cancer (mean 5.59, p = 0.43). It was worse than patients surveyed with breast cancer (mean 6.51, p < 0.01).

conclusionsWe found the self-reported QOL of thyroid cancer survivors in our study population is overall similar to or worse than that of survivors of other types of cancer surveyed with the same instrument. This should heighten awareness of the significance of a thyroid cancer diagnosis and highlights the need for further research in how to improve care for this enlarging group of patients.

Indexed as

Global HealthHumansIncidenceNeoplasmsQuality of LifeSurveys and QuestionnairesSurvival RateSurvivorsThyroid Neoplasms

Identifiers

PMID26546191
OpenAlexW2153801799

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.