ArticleWorld journal of surgery2016
Characteristics of Persistent Hyperparathyroidism After Renal Transplantation.
Article in World journal of surgery, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.
- Endocrine surgery during and after the COVID-19 epidemic: Expert guidelines from AFCE.Journal of visceral surgery · 2020Guideline
- The Prevalence and Risk Factors for Persistent Hyperparathyroidism in Post-Kidney Transplant Patients: A Single-Center Retrospective Study.Journal of the ASEAN Federation of Endocrine Societies · 2026Article
- Persistent hyperparathyroidism after kidney transplantation in children.Renal failure · 2025Article
- Review
- Association of Coronary Calcium Score on Cardiac PET During Pre-Kidney Transplant Assessment with Persistent Hyperparathyroidism: A Retrospective Study.Annals of transplantation · 2024Article
- Pre-Transplant Calcimimetic Use and Dose Information Improves the Accuracy of Prediction of Tertiary Hyperparathyroidism after Kidney Transplantation: A Retrospective Cohort Study.Transplant international : official journal of the European Society for Organ Transplantation · 2024Article
- Persistent hyperparathyroidism after preemptive kidney transplantation.Clinical and experimental nephrology · 2023Article
- Systematic Review of the Treatment of Persistent Hyperparathyroidism Following Kidney Transplantation.Biomedicines · 2022Review
- Impact of parathyroidectomy on kidney graft function in post-transplant tertiary hyperparathyroidism: a comparative study.Langenbeck's archives of surgery · 2022Article
- A roadmap to parathyroidectomy for kidney transplant candidates.Clinical kidney journal · 2022Review
- Clinical Prediction of High-Turnover Bone Disease After Kidney Transplantation.Calcified tissue international · 2022Article
- Prevalence and risk factors for tertiary hyperparathyroidism in kidney transplant recipients.Surgery · 2022Observational
- Parathyroidectomy for tertiary hyperparathyroidism after second kidney transplantation: a case report.CEN case reports · 2021Article
- Effect of Pretransplant Use of Calcimimetic on Parathyroid Function after Renal Transplantation.International journal of endocrinology · 2021Article
- [Endocrine surgery during and after the COVID-19 epidemic: Guidelines from AFCE].Journal de chirurgie viscerale · 2020Review
- Comparison of Pre- and Post-transplant Parathyroidectomy in Renal Transplant Recipients and the Impact of Parathyroidectomy Timing on Calcium Metabolism and Renal Allograft Function: A Retrospective Single-Center Analysis.World journal of surgery · 2020Article
- Vitamin D-Mediated Hypercalcemia: Mechanisms, Diagnosis, and Treatment.Endocrine reviews · 2016Review
- Initial surgical results of 500 Parathyroidectomies for Hyperparathyroidism related to chronic kidney disease - mineral and bone disorder.Jornal brasileiro de nefrologiaArticle
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPersistent hyperparathyroidism (HPT) after renal transplantation (RTx), termed tertiary HPT (THPT), is not uncommon. However, risk factors and appropriate operative procedures for THPT are poorly understood.
methodsA retrospective study of patients who underwent RTx without pre-transplant parathyroidectomy (PTx) was performed at our hospital between January 2001 and March 2011. Risk factors for the development of THPT were investigated by comparing THPT and non-THPT groups. We retrospectively analyzed patients with THPT who underwent total PTx with forearm autograft. Pre- and postoperative (1 year after PTx) laboratory results were analyzed for PTx efficacy.
resultsData for 520 patients were analyzed. On multivariate analysis, long dialysis duration (p = 0.009, hazard ratio (HR) 1.01), large maximum parathyroid gland size before RTx (p = 0.003, HR 1.23), pre-RTx high intact parathyroid hormone (iPTH) (p = 0.041, HR 1.01), post-RTx (<2 weeks) high calcium (Ca) (p < 0.001, HR 25.04), and post-RTx high alkaline phosphatase (ALP) (p = 0.027, HR 0.99) were identified as risk factors for THPT. Patients who underwent PTx showed significant improvement compared with baseline for serum Ca, phosphorus, iPTH, and ALP. Serum creatinine showed no significant difference.
conclusionsSeveral risk factors for THPT development were identified. PTx for patients with THPT significantly improved serum Ca, iPTH, ALP, and phosphorous levels. There was no significant difference in renal function after PTx. Therefore, total PTx with forearm autograft may be an appropriate surgical approach for patients with THPT.
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