Evidence map›Paper›PMID 26546040›Full record

ReviewDifferentiation; research in biological diversity

Isolation and analysis of discreet human prostate cellular populations.

Douglas W Strand, LaTayia Aaron, Gervaise Henry, Omar E Franco, Simon W Hayward

Open access · greenAbstract readReview
In one paragraph

Review in Differentiation; research in biological diversity. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
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  12. Review
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  15. Article
  16. OMIP-040: Optimized gating of human prostate cellular subpopulations.Cytometry. Part A : the journal of the International Society for Analytical Cytology · 2017
    Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Douglas W StrandDepartment of Urology, UT Southwestern University Medical Center, Dallas, TX, USA.
LaTayia AaronDepartment of Cancer Biology, Meharry Medical College, Nashville, TN, USA.
Gervaise HenryDepartment of Urology, UT Southwestern University Medical Center, Dallas, TX, USA.
Omar E FrancoDepartment of Surgery, NorthShore University Health System, Research Institute, Evanston, IL, USA.
Simon W HaywardDepartment of Surgery, NorthShore University Health System, Research Institute, Evanston, IL, USA. Electronic address: shayward@northshore.org.
NorthShore University HealthSystem · USMeharry Medical College · USSouthwestern University · USUniversity Medical Center · US

Funding

The Vanderbilt Institute for Clinical and Translational Research (VICTR)UL1TR000445 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BERNARD, GORDON RAPHAEL · 2012 to 2016
$41.4M
THE MEHARRY RISE INITIATIVER25GM059994 · NIGMS · MEHARRY MEDICAL COLLEGE · PI MOTLEY-JOHNSON, EVANGELINE D · 1999 to 2021
$23.0M
Meharry RCMI Program in Women's Health ResearchG12MD007586 · NIMHD · MEHARRY MEDICAL COLLEGE · PI HILDRETH, JAMES E · 2012 to 2016
$7.8M
AP-1 Factors in the Pathogenesis and Progression of Benign Prostatic HyperplasiaR01DK103483 · NIDDK · VANDERBILT UNIVERSITY · PI HAYWARD, SIMON W · 2014 to 2017
$1.3M
Mechanisms of Fatty Acid Metabolism in Prostate Differentiation and DiseaseK01DK098277 · NIDDK · VANDERBILT UNIVERSITY · PI STRAND, DOUGLAS WILLIAM · 2013 to 2017
$640k
NCATS NIH HHS UL1 TR000445NIDDK NIH HHS K01 DK098277NIDDK NIH HHS R01 DK103483NIGMS NIH HHS R25 GM059994NIMHD NIH HHS G12 MD007586
6 · The paper itself

Abstract

The use of lineage tracing in transgenic mouse models has revealed an abundance of subcellular phenotypes responsible for maintaining prostate homeostasis. The ability to use fresh human tissues to examine the hypotheses generated by these mouse experiments has been greatly enhanced by technical advances in tissue processing, flow cytometry and cell culture. We describe in detail the optimization of protocols for each of these areas to facilitate research on solving human prostate diseases through the analysis of human tissue.

Indexed as

AnimalsCell DifferentiationCell SeparationEpithelial CellsFlow CytometryHumansMaleMiceMice, TransgenicProstate

Identifiers

PMID26546040
PMCPMC4854811
OpenAlexW2194261584

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.